Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen

The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.

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Autores principales:	Alastair Muir, Ishwori Gurung, Ana Cehovin, Adelme Bazin, David Vallenet, Vladimir Pelicic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d95231864c5047f889a4063e8d65f361
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spelling	oai:doaj.org-article:d95231864c5047f889a4063e8d65f3612021-12-02T15:39:10ZConstruction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen10.1038/s41467-020-19347-y2041-1723https://doaj.org/article/d95231864c5047f889a4063e8d65f3612020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19347-yhttps://doaj.org/toc/2041-1723The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.Alastair MuirIshwori GurungAna CehovinAdelme BazinDavid VallenetVladimir PelicicNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alastair Muir Ishwori Gurung Ana Cehovin Adelme Bazin David Vallenet Vladimir Pelicic Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
description	The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.
format	article
author	Alastair Muir Ishwori Gurung Ana Cehovin Adelme Bazin David Vallenet Vladimir Pelicic
author_facet	Alastair Muir Ishwori Gurung Ana Cehovin Adelme Bazin David Vallenet Vladimir Pelicic
author_sort	Alastair Muir
title	Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
title_short	Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
title_full	Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
title_fullStr	Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
title_full_unstemmed	Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
title_sort	construction of a complete set of neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d95231864c5047f889a4063e8d65f361
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Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen

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