Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.
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Autores principales: | Alastair Muir, Ishwori Gurung, Ana Cehovin, Adelme Bazin, David Vallenet, Vladimir Pelicic |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/d95231864c5047f889a4063e8d65f361 |
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