Autoantibodies to estrogen receptor α in systemic sclerosis (SSc) as pathogenetic determinants and markers of progression.
Systemic sclerosis (SSc) is a multisystem autoimmune disease of unknown etiology characterized by inflammation, autoantibody production, and fibrosis. It predominantly affects women, this suggesting that female sex hormones such as estrogens may play a role in disease pathogenesis. However, up to da...
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Autores principales: | Antonello Giovannetti, Angela Maselli, Tania Colasanti, Edoardo Rosato, Felice Salsano, Simonetta Pisarri, Ivano Mezzaroma, Walter Malorni, Elena Ortona, Marina Pierdominici |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/d95940a4f5fa4b2ba1ed026699ada411 |
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