“CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME

Sixty-eight patients with acute coronary syndrome (ACS) were studied for correlations between the levels of interleukin IL-6 and IL-10 in blood and saliva, highly sensitive C-reactive protein (hs-CRP) and brain natriuretic peptide (NtproBNP) in the blood serum with the development of cardiovascular...

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Autores principales: E. T. Manyukova, M. A. Shalenkova, Z. D. Mikhailova
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Lenguaje:RU
Publicado: SPb RAACI 2015
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Acceso en línea:https://doaj.org/article/d95e97016cfb49cab375cddf5cafac57
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spelling oai:doaj.org-article:d95e97016cfb49cab375cddf5cafac572021-11-18T08:03:44Z“CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME1563-06252313-741X10.15789/1563-0625-2015-1-81-86https://doaj.org/article/d95e97016cfb49cab375cddf5cafac572015-03-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/812https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XSixty-eight patients with acute coronary syndrome (ACS) were studied for correlations between the levels of interleukin IL-6 and IL-10 in blood and saliva, highly sensitive C-reactive protein (hs-CRP) and brain natriuretic peptide (NtproBNP) in the blood serum with the development of cardiovascular complications (CVC) during hospital period of the disease. It has been revealed that the patients with CVC had higher concentration of IL-6 in blood, IL-6, IL-10 in saliva, hs-CRP and NtproBNP in blood samples. Meanwhile, excess of IL-6 levels in saliva over those in blood was a significant predictor of CVC development. In order to facilitate the prediction values of CVC during ACS hospital period we have proposed a “CVCACS” model that employed the parameters of patient’s age, IL-10 level in the saliva, IL-6, and hs-CRP amounts in blood. It should be mentioned that the variable value of > -0,657 obtained with “CVCACS” model was predictive for development of CVC during ACS hospital period, while ≤ -0,657 was associated with favorable course of ACS hospital period.E. T. ManyukovaM. A. ShalenkovaZ. D. MikhailovaSPb RAACIarticleinterleukin-6interleukin-10highly sensitive c-reactive proteincardiovascular complicationsacute coronary syndromeImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 17, Iss 1, Pp 81-86 (2015)
institution DOAJ
collection DOAJ
language RU
topic interleukin-6
interleukin-10
highly sensitive c-reactive protein
cardiovascular complications
acute coronary syndrome
Immunologic diseases. Allergy
RC581-607
spellingShingle interleukin-6
interleukin-10
highly sensitive c-reactive protein
cardiovascular complications
acute coronary syndrome
Immunologic diseases. Allergy
RC581-607
E. T. Manyukova
M. A. Shalenkova
Z. D. Mikhailova
“CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
description Sixty-eight patients with acute coronary syndrome (ACS) were studied for correlations between the levels of interleukin IL-6 and IL-10 in blood and saliva, highly sensitive C-reactive protein (hs-CRP) and brain natriuretic peptide (NtproBNP) in the blood serum with the development of cardiovascular complications (CVC) during hospital period of the disease. It has been revealed that the patients with CVC had higher concentration of IL-6 in blood, IL-6, IL-10 in saliva, hs-CRP and NtproBNP in blood samples. Meanwhile, excess of IL-6 levels in saliva over those in blood was a significant predictor of CVC development. In order to facilitate the prediction values of CVC during ACS hospital period we have proposed a “CVCACS” model that employed the parameters of patient’s age, IL-10 level in the saliva, IL-6, and hs-CRP amounts in blood. It should be mentioned that the variable value of > -0,657 obtained with “CVCACS” model was predictive for development of CVC during ACS hospital period, while ≤ -0,657 was associated with favorable course of ACS hospital period.
format article
author E. T. Manyukova
M. A. Shalenkova
Z. D. Mikhailova
author_facet E. T. Manyukova
M. A. Shalenkova
Z. D. Mikhailova
author_sort E. T. Manyukova
title “CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
title_short “CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
title_full “CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
title_fullStr “CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
title_full_unstemmed “CVCACS” MODEL FOR PREDICTION OF CARDIOVASCULAR COMPLICATIONS IN HOSPITALIZED PATIENTS WITH ACUTE CORONARY SYNDROME
title_sort “cvcacs” model for prediction of cardiovascular complications in hospitalized patients with acute coronary syndrome
publisher SPb RAACI
publishDate 2015
url https://doaj.org/article/d95e97016cfb49cab375cddf5cafac57
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AT mashalenkova cvcacsmodelforpredictionofcardiovascularcomplicationsinhospitalizedpatientswithacutecoronarysyndrome
AT zdmikhailova cvcacsmodelforpredictionofcardiovascularcomplicationsinhospitalizedpatientswithacutecoronarysyndrome
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