Assessing predictors of changes in protein stability upon mutation using self-consistency.
The ability to predict the effect of mutations on protein stability is important for a wide range of tasks, from protein engineering to assessing the impact of SNPs to understanding basic protein biophysics. A number of methods have been developed that make these predictions, but assessing the accur...
Guardado en:
Autores principales: | Grant Thiltgen, Richard A Goldstein |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/d963bfca1cf040979378049acd78eed1 |
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