Assessing predictors of changes in protein stability upon mutation using self-consistency.

The ability to predict the effect of mutations on protein stability is important for a wide range of tasks, from protein engineering to assessing the impact of SNPs to understanding basic protein biophysics. A number of methods have been developed that make these predictions, but assessing the accur...

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Autores principales: Grant Thiltgen, Richard A Goldstein
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d963bfca1cf040979378049acd78eed1
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