SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis

Stress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts.

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Detalles Bibliográficos
Autores principales: Minhoo Kim, Yoonjung Choi, Harim Kim, Daeyoup Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d96b862436bc4a378374a714644eafc6
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Sumario:Stress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts.