Orchestrated ensemble activities constitute a hippocampal memory engram

The brain stores memories through a set of neurons known as engram cells. Here, the authors show that engram cells in the mouse hippocampus are organized into sub-ensembles representing distinct pieces of information, which are then orchestrated to constitute an entire memory.

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Autores principales: Khaled Ghandour, Noriaki Ohkawa, Chi Chung Alan Fung, Hirotaka Asai, Yoshito Saitoh, Takashi Takekawa, Reiko Okubo-Suzuki, Shingo Soya, Hirofumi Nishizono, Mina Matsuo, Makoto Osanai, Masaaki Sato, Masamichi Ohkura, Junichi Nakai, Yasunori Hayashi, Takeshi Sakurai, Takashi Kitamura, Tomoki Fukai, Kaoru Inokuchi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d96ece91fcd34bc6904590181d831291
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spelling oai:doaj.org-article:d96ece91fcd34bc6904590181d8312912021-12-02T17:01:31ZOrchestrated ensemble activities constitute a hippocampal memory engram10.1038/s41467-019-10683-22041-1723https://doaj.org/article/d96ece91fcd34bc6904590181d8312912019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10683-2https://doaj.org/toc/2041-1723The brain stores memories through a set of neurons known as engram cells. Here, the authors show that engram cells in the mouse hippocampus are organized into sub-ensembles representing distinct pieces of information, which are then orchestrated to constitute an entire memory.Khaled GhandourNoriaki OhkawaChi Chung Alan FungHirotaka AsaiYoshito SaitohTakashi TakekawaReiko Okubo-SuzukiShingo SoyaHirofumi NishizonoMina MatsuoMakoto OsanaiMasaaki SatoMasamichi OhkuraJunichi NakaiYasunori HayashiTakeshi SakuraiTakashi KitamuraTomoki FukaiKaoru InokuchiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Khaled Ghandour
Noriaki Ohkawa
Chi Chung Alan Fung
Hirotaka Asai
Yoshito Saitoh
Takashi Takekawa
Reiko Okubo-Suzuki
Shingo Soya
Hirofumi Nishizono
Mina Matsuo
Makoto Osanai
Masaaki Sato
Masamichi Ohkura
Junichi Nakai
Yasunori Hayashi
Takeshi Sakurai
Takashi Kitamura
Tomoki Fukai
Kaoru Inokuchi
Orchestrated ensemble activities constitute a hippocampal memory engram
description The brain stores memories through a set of neurons known as engram cells. Here, the authors show that engram cells in the mouse hippocampus are organized into sub-ensembles representing distinct pieces of information, which are then orchestrated to constitute an entire memory.
format article
author Khaled Ghandour
Noriaki Ohkawa
Chi Chung Alan Fung
Hirotaka Asai
Yoshito Saitoh
Takashi Takekawa
Reiko Okubo-Suzuki
Shingo Soya
Hirofumi Nishizono
Mina Matsuo
Makoto Osanai
Masaaki Sato
Masamichi Ohkura
Junichi Nakai
Yasunori Hayashi
Takeshi Sakurai
Takashi Kitamura
Tomoki Fukai
Kaoru Inokuchi
author_facet Khaled Ghandour
Noriaki Ohkawa
Chi Chung Alan Fung
Hirotaka Asai
Yoshito Saitoh
Takashi Takekawa
Reiko Okubo-Suzuki
Shingo Soya
Hirofumi Nishizono
Mina Matsuo
Makoto Osanai
Masaaki Sato
Masamichi Ohkura
Junichi Nakai
Yasunori Hayashi
Takeshi Sakurai
Takashi Kitamura
Tomoki Fukai
Kaoru Inokuchi
author_sort Khaled Ghandour
title Orchestrated ensemble activities constitute a hippocampal memory engram
title_short Orchestrated ensemble activities constitute a hippocampal memory engram
title_full Orchestrated ensemble activities constitute a hippocampal memory engram
title_fullStr Orchestrated ensemble activities constitute a hippocampal memory engram
title_full_unstemmed Orchestrated ensemble activities constitute a hippocampal memory engram
title_sort orchestrated ensemble activities constitute a hippocampal memory engram
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d96ece91fcd34bc6904590181d831291
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