Surface Characterization of Lipid Biomimetic Systems

Zeta potential and dipole potential measures are direct operational methodologies to determine the adsorption, insertion and penetration of ions, amphipathic and neutral compounds into the membranes of cells and model systems. From these results, the contribution of charged and dipole groups can be...

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Autores principales:	Anibal Disalvo, Maria A. Frias
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	lipid membranes biomimetic systems hydration dipole potential zeta potential Chemical technology TP1-1185 Chemical engineering TP155-156
Acceso en línea:	https://doaj.org/article/d9783ba3edef4c4599d00840bbdab6b7
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id	oai:doaj.org-article:d9783ba3edef4c4599d00840bbdab6b7
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spelling	oai:doaj.org-article:d9783ba3edef4c4599d00840bbdab6b72021-11-25T18:19:35ZSurface Characterization of Lipid Biomimetic Systems10.3390/membranes111108212077-0375https://doaj.org/article/d9783ba3edef4c4599d00840bbdab6b72021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0375/11/11/821https://doaj.org/toc/2077-0375Zeta potential and dipole potential measures are direct operational methodologies to determine the adsorption, insertion and penetration of ions, amphipathic and neutral compounds into the membranes of cells and model systems. From these results, the contribution of charged and dipole groups can be deduced. However, although each method may give apparent affinity or binding constants, care should be taken to interpret them in terms of physical meaning because they are not independent properties. On the base of a recent model in which the lipid bilayer is considered as composed by two interphase regions at each side of the hydrocarbon core, this review describes how dipole potential and zeta potential are correlated due to water reorganization. From this analysis, considering that in a cell the interphase region the membrane extends to the cell interior or overlaps with the interphase region of another supramolecular structure, the correlation of dipole and electrostatic forces can be taken as responsible of the propagation of perturbations between membrane and cytoplasm and vice versa. Thus, this picture gives the membrane a responsive character in addition to that of a selective permeability barrier when integrated to a complex system.Anibal DisalvoMaria A. FriasMDPI AGarticlelipid membranesbiomimetic systemshydrationdipole potentialzeta potentialChemical technologyTP1-1185Chemical engineeringTP155-156ENMembranes, Vol 11, Iss 821, p 821 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lipid membranes biomimetic systems hydration dipole potential zeta potential Chemical technology TP1-1185 Chemical engineering TP155-156
spellingShingle	lipid membranes biomimetic systems hydration dipole potential zeta potential Chemical technology TP1-1185 Chemical engineering TP155-156 Anibal Disalvo Maria A. Frias Surface Characterization of Lipid Biomimetic Systems
description	Zeta potential and dipole potential measures are direct operational methodologies to determine the adsorption, insertion and penetration of ions, amphipathic and neutral compounds into the membranes of cells and model systems. From these results, the contribution of charged and dipole groups can be deduced. However, although each method may give apparent affinity or binding constants, care should be taken to interpret them in terms of physical meaning because they are not independent properties. On the base of a recent model in which the lipid bilayer is considered as composed by two interphase regions at each side of the hydrocarbon core, this review describes how dipole potential and zeta potential are correlated due to water reorganization. From this analysis, considering that in a cell the interphase region the membrane extends to the cell interior or overlaps with the interphase region of another supramolecular structure, the correlation of dipole and electrostatic forces can be taken as responsible of the propagation of perturbations between membrane and cytoplasm and vice versa. Thus, this picture gives the membrane a responsive character in addition to that of a selective permeability barrier when integrated to a complex system.
format	article
author	Anibal Disalvo Maria A. Frias
author_facet	Anibal Disalvo Maria A. Frias
author_sort	Anibal Disalvo
title	Surface Characterization of Lipid Biomimetic Systems
title_short	Surface Characterization of Lipid Biomimetic Systems
title_full	Surface Characterization of Lipid Biomimetic Systems
title_fullStr	Surface Characterization of Lipid Biomimetic Systems
title_full_unstemmed	Surface Characterization of Lipid Biomimetic Systems
title_sort	surface characterization of lipid biomimetic systems
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/d9783ba3edef4c4599d00840bbdab6b7
work_keys_str_mv	AT anibaldisalvo surfacecharacterizationoflipidbiomimeticsystems AT mariaafrias surfacecharacterizationoflipidbiomimeticsystems
_version_	1718411349868937216

Surface Characterization of Lipid Biomimetic Systems

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