Serious complications of COVID-19 vaccines: A mini-review

Τhe most promising approach of fighting COVID-19 and restraining the course of this pandemic is indisputably the universal vaccination of the population with safe and effective vaccines. However, besides the common and usually mild side effects of the authorized vaccines, some rare, major adverse re...

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Autores principales:	Paraskevi C. Fragkou, Dimitra Dimopoulou
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	COVID-19 Vaccines Complications Adverse events Physiology QP1-981 Biochemistry QD415-436
Acceso en línea:	https://doaj.org/article/d97a5637374c4319907a7366320eba1d
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spelling	oai:doaj.org-article:d97a5637374c4319907a7366320eba1d2021-11-04T04:38:53ZSerious complications of COVID-19 vaccines: A mini-review2589-936810.1016/j.metop.2021.100145https://doaj.org/article/d97a5637374c4319907a7366320eba1d2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2589936821000694https://doaj.org/toc/2589-9368Τhe most promising approach of fighting COVID-19 and restraining the course of this pandemic is indisputably the universal vaccination of the population with safe and effective vaccines. However, besides the common and usually mild side effects of the authorized vaccines, some rare, major adverse reactions are increasingly being reported worldwide during the post marketing surveillance phase of vaccines’ circulation, such as anaphylaxis, vaccine-induced thrombotic thrombocytopenia, myopericarditis and Guillain-Barré syndrome. Despite rare cases with complications from COVID-19 vaccines, the net benefit-risk ratio shows a clearly favorable balance towards COVID-19 vaccination for all age and sex groups. Vaccine adverse events should be identified early and monitored closely. As many aspects of these adverse effects remain still obscure for the medical community and the relevant stakeholders, it is also highly important to be promptly reported. Nonetheless, these complications should not constitute a reason to change the vaccine policy and further studies are needed to alleviate concerns and reluctance to COVID-19 vaccinations.Paraskevi C. FragkouDimitra DimopoulouElsevierarticleCOVID-19VaccinesComplicationsAdverse eventsPhysiologyQP1-981BiochemistryQD415-436ENMetabolism Open, Vol 12, Iss , Pp 100145- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 Vaccines Complications Adverse events Physiology QP1-981 Biochemistry QD415-436
spellingShingle	COVID-19 Vaccines Complications Adverse events Physiology QP1-981 Biochemistry QD415-436 Paraskevi C. Fragkou Dimitra Dimopoulou Serious complications of COVID-19 vaccines: A mini-review
description	Τhe most promising approach of fighting COVID-19 and restraining the course of this pandemic is indisputably the universal vaccination of the population with safe and effective vaccines. However, besides the common and usually mild side effects of the authorized vaccines, some rare, major adverse reactions are increasingly being reported worldwide during the post marketing surveillance phase of vaccines’ circulation, such as anaphylaxis, vaccine-induced thrombotic thrombocytopenia, myopericarditis and Guillain-Barré syndrome. Despite rare cases with complications from COVID-19 vaccines, the net benefit-risk ratio shows a clearly favorable balance towards COVID-19 vaccination for all age and sex groups. Vaccine adverse events should be identified early and monitored closely. As many aspects of these adverse effects remain still obscure for the medical community and the relevant stakeholders, it is also highly important to be promptly reported. Nonetheless, these complications should not constitute a reason to change the vaccine policy and further studies are needed to alleviate concerns and reluctance to COVID-19 vaccinations.
format	article
author	Paraskevi C. Fragkou Dimitra Dimopoulou
author_facet	Paraskevi C. Fragkou Dimitra Dimopoulou
author_sort	Paraskevi C. Fragkou
title	Serious complications of COVID-19 vaccines: A mini-review
title_short	Serious complications of COVID-19 vaccines: A mini-review
title_full	Serious complications of COVID-19 vaccines: A mini-review
title_fullStr	Serious complications of COVID-19 vaccines: A mini-review
title_full_unstemmed	Serious complications of COVID-19 vaccines: A mini-review
title_sort	serious complications of covid-19 vaccines: a mini-review
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/d97a5637374c4319907a7366320eba1d
work_keys_str_mv	AT paraskevicfragkou seriouscomplicationsofcovid19vaccinesaminireview AT dimitradimopoulou seriouscomplicationsofcovid19vaccinesaminireview
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Serious complications of COVID-19 vaccines: A mini-review

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