The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia

I-Hung Shao,1,* Chen-Pang Hou,1,* Shao-Ming Chen,3 Chien-Lun Chen,1,2 Yu-Hsiang Lin,1 Phei-Lang Chang,1,2 Ke-Hung Tsui1,2 1Department of Urology, 2Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine, 3Department of Urology, Taipei City Hospital, He...

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Autores principales: Shao IH, Hou CP, Chen SM, Chen CL, Lin YH, Chang PL, Tsui KH
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:d97d518c17984bbbbd31a8d5c4b9eedf2021-12-02T00:12:05ZThe safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia1178-1998https://doaj.org/article/d97d518c17984bbbbd31a8d5c4b9eedf2013-03-01T00:00:00Zhttps://www.dovepress.com/the-safety-and-efficacy-of-aspirin-intake-in-photoselective-vaporizati-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998I-Hung Shao,1,* Chen-Pang Hou,1,* Shao-Ming Chen,3 Chien-Lun Chen,1,2 Yu-Hsiang Lin,1 Phei-Lang Chang,1,2 Ke-Hung Tsui1,2 1Department of Urology, 2Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine, 3Department of Urology, Taipei City Hospital, Heping Campus, Taipei, Taiwan, People's Republic of China *These authors contributed equally to this work Abstract: Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse events up to 12 months postoperatively of patients on oral anticoagulation therapy undergoing PVP, and compared the results with patients who did not take anticoagulation therapy. A total of 89 patients who received photoselective vaporization laser for benign prostate hyperplasia from May 2006 to February 2011 in our hospital were enrolled in our study. The patients were divided into two groups based on whether or not they were taking oral aspirin; 23 (25.8%) patients were taking aspirin derivatives (aspirin group), and 66 (74.2%) were not taking aspirin derivatives (control group). The mean prostate volume (58.8 mL vs 51 mL; P = 0.16) and mean energy consumption (235,268 J vs 289,793 J; P = 0.097) were comparable between the aspirin group and control group. The average postoperative results of hemoglobin were 13.4 mg/dL for the aspirin group versus 13.9 mg/dL for the control group (P = 0.327). A significantly higher maximum flow rates and 80% improved post-void residual urine were noted during the followup. Postoperatively all variable showed significant improvement starting at month 1 of followup and remained improved for the 12 month followup. Postoperative complications were low and comparable between groups. PVP was characterized by excellent hemostatic properties and a very low intraoperative complication rate, even in the patients who were taking aspirin. On the basis of our perioperative results, we recommend PVP as a safe and effective procedure for patients with symptomatic benign prostate hyperplasia when taking an aspirin derivative. Keywords: prostate gland, benign prostatic hyperplasia, laser, elderly, green light laser Corrigendum for this paper has been publishedShao IHHou CPChen SMChen CLLin YHChang PLTsui KHDove Medical Pressarticleprostate glandbenign prostatic hyperplasialaserelderlygreen light laserGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 8, Pp 265-269 (2013)
institution DOAJ
collection DOAJ
language EN
topic prostate gland
benign prostatic hyperplasia
laser
elderly
green light laser
Geriatrics
RC952-954.6
spellingShingle prostate gland
benign prostatic hyperplasia
laser
elderly
green light laser
Geriatrics
RC952-954.6
Shao IH
Hou CP
Chen SM
Chen CL
Lin YH
Chang PL
Tsui KH
The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
description I-Hung Shao,1,* Chen-Pang Hou,1,* Shao-Ming Chen,3 Chien-Lun Chen,1,2 Yu-Hsiang Lin,1 Phei-Lang Chang,1,2 Ke-Hung Tsui1,2 1Department of Urology, 2Bioinformation Center, Chang Gung Memorial Hospital-Linko and Chang Gung University College of Medicine, 3Department of Urology, Taipei City Hospital, Heping Campus, Taipei, Taiwan, People's Republic of China *These authors contributed equally to this work Abstract: Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse events up to 12 months postoperatively of patients on oral anticoagulation therapy undergoing PVP, and compared the results with patients who did not take anticoagulation therapy. A total of 89 patients who received photoselective vaporization laser for benign prostate hyperplasia from May 2006 to February 2011 in our hospital were enrolled in our study. The patients were divided into two groups based on whether or not they were taking oral aspirin; 23 (25.8%) patients were taking aspirin derivatives (aspirin group), and 66 (74.2%) were not taking aspirin derivatives (control group). The mean prostate volume (58.8 mL vs 51 mL; P = 0.16) and mean energy consumption (235,268 J vs 289,793 J; P = 0.097) were comparable between the aspirin group and control group. The average postoperative results of hemoglobin were 13.4 mg/dL for the aspirin group versus 13.9 mg/dL for the control group (P = 0.327). A significantly higher maximum flow rates and 80% improved post-void residual urine were noted during the followup. Postoperatively all variable showed significant improvement starting at month 1 of followup and remained improved for the 12 month followup. Postoperative complications were low and comparable between groups. PVP was characterized by excellent hemostatic properties and a very low intraoperative complication rate, even in the patients who were taking aspirin. On the basis of our perioperative results, we recommend PVP as a safe and effective procedure for patients with symptomatic benign prostate hyperplasia when taking an aspirin derivative. Keywords: prostate gland, benign prostatic hyperplasia, laser, elderly, green light laser Corrigendum for this paper has been published
format article
author Shao IH
Hou CP
Chen SM
Chen CL
Lin YH
Chang PL
Tsui KH
author_facet Shao IH
Hou CP
Chen SM
Chen CL
Lin YH
Chang PL
Tsui KH
author_sort Shao IH
title The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
title_short The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
title_full The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
title_fullStr The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
title_full_unstemmed The safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
title_sort safety and efficacy of aspirin intake in photoselective vaporization laser treatment of benign prostate hyperplasia
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/d97d518c17984bbbbd31a8d5c4b9eedf
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