Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA

Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoter...

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Autores principales: Wooyoung Kang, Kook Sun Ha, Heesoo Uhm, Kyuhyong Park, Ja Yil Lee, Sungchul Hohng, Changwon Kang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c
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spelling oai:doaj.org-article:d97e30411e7f425eab5086b9c09f7d1c2021-12-02T17:31:57ZTranscription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA10.1038/s41467-019-14200-32041-1723https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14200-3https://doaj.org/toc/2041-1723Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoters.Wooyoung KangKook Sun HaHeesoo UhmKyuhyong ParkJa Yil LeeSungchul HohngChangwon KangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wooyoung Kang
Kook Sun Ha
Heesoo Uhm
Kyuhyong Park
Ja Yil Lee
Sungchul Hohng
Changwon Kang
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
description Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoters.
format article
author Wooyoung Kang
Kook Sun Ha
Heesoo Uhm
Kyuhyong Park
Ja Yil Lee
Sungchul Hohng
Changwon Kang
author_facet Wooyoung Kang
Kook Sun Ha
Heesoo Uhm
Kyuhyong Park
Ja Yil Lee
Sungchul Hohng
Changwon Kang
author_sort Wooyoung Kang
title Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
title_short Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
title_full Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
title_fullStr Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
title_full_unstemmed Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
title_sort transcription reinitiation by recycling rna polymerase that diffuses on dna after releasing terminated rna
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c
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