Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoter...
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2020
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oai:doaj.org-article:d97e30411e7f425eab5086b9c09f7d1c2021-12-02T17:31:57ZTranscription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA10.1038/s41467-019-14200-32041-1723https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14200-3https://doaj.org/toc/2041-1723Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoters.Wooyoung KangKook Sun HaHeesoo UhmKyuhyong ParkJa Yil LeeSungchul HohngChangwon KangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Wooyoung Kang Kook Sun Ha Heesoo Uhm Kyuhyong Park Ja Yil Lee Sungchul Hohng Changwon Kang Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
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Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining RNA polymerase can reinitiate at nearby promoters. |
format |
article |
author |
Wooyoung Kang Kook Sun Ha Heesoo Uhm Kyuhyong Park Ja Yil Lee Sungchul Hohng Changwon Kang |
author_facet |
Wooyoung Kang Kook Sun Ha Heesoo Uhm Kyuhyong Park Ja Yil Lee Sungchul Hohng Changwon Kang |
author_sort |
Wooyoung Kang |
title |
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
title_short |
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
title_full |
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
title_fullStr |
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
title_full_unstemmed |
Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA |
title_sort |
transcription reinitiation by recycling rna polymerase that diffuses on dna after releasing terminated rna |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c |
work_keys_str_mv |
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1718380461979336704 |