Bis-silylation of internal alkynes enabled by Ni(0) catalysis
Bis-silylated alkenes offer the advantage of two functional handles with distinguished reactivity for downstream functionalization. Here, the authors report a nickel-catalyzed bis-silylation of internal alkynes to versatile silylated alkene intermediates which can be chemoselectively manipulated.
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/d98163b8a0ff4e948f20431981c2b554 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Bis-silylated alkenes offer the advantage of two functional handles with distinguished reactivity for downstream functionalization. Here, the authors report a nickel-catalyzed bis-silylation of internal alkynes to versatile silylated alkene intermediates which can be chemoselectively manipulated. |
|---|