Allostery through DNA drives phenotype switching
Most insights on DNA-mediated allostery upon transcription factor (TF) binding were either based on artificial promoters or found to be short-ranged. Here authors use single-molecule FRET and cryo-EM to show that Bacillus subtilis bacteria utilize long-range allostery in a stochastic and reversible...
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Auteurs principaux: | Gabriel Rosenblum, Nadav Elad, Haim Rozenberg, Felix Wiggers, Jakub Jungwirth, Hagen Hofmann |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/d98248e72e7a43afad2cce3d9fb3924e |
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