Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating

Mathelié-Guinlet et al. investigate the molecular binding mechanisms of sexual agglutinins in budding yeast Saccharomyces cerevisiae. They report that mechanical tension enhances the strength of agglutinin interactions, supporting a new model in which physical stress induces conformational changes i...

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Autores principales: Marion Mathelié-Guinlet, Felipe Viela, Jérôme Dehullu, Sviatlana Filimonava, Jason M. Rauceo, Peter N. Lipke, Yves F. Dufrêne
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d982771433c549ee97383aaeb1e7498c
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spelling oai:doaj.org-article:d982771433c549ee97383aaeb1e7498c2021-12-02T15:13:13ZSingle-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating10.1038/s42003-020-01498-92399-3642https://doaj.org/article/d982771433c549ee97383aaeb1e7498c2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01498-9https://doaj.org/toc/2399-3642Mathelié-Guinlet et al. investigate the molecular binding mechanisms of sexual agglutinins in budding yeast Saccharomyces cerevisiae. They report that mechanical tension enhances the strength of agglutinin interactions, supporting a new model in which physical stress induces conformational changes in the binding sites of agglutinins.Marion Mathelié-GuinletFelipe VielaJérôme DehulluSviatlana FilimonavaJason M. RauceoPeter N. LipkeYves F. DufrêneNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Marion Mathelié-Guinlet
Felipe Viela
Jérôme Dehullu
Sviatlana Filimonava
Jason M. Rauceo
Peter N. Lipke
Yves F. Dufrêne
Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
description Mathelié-Guinlet et al. investigate the molecular binding mechanisms of sexual agglutinins in budding yeast Saccharomyces cerevisiae. They report that mechanical tension enhances the strength of agglutinin interactions, supporting a new model in which physical stress induces conformational changes in the binding sites of agglutinins.
format article
author Marion Mathelié-Guinlet
Felipe Viela
Jérôme Dehullu
Sviatlana Filimonava
Jason M. Rauceo
Peter N. Lipke
Yves F. Dufrêne
author_facet Marion Mathelié-Guinlet
Felipe Viela
Jérôme Dehullu
Sviatlana Filimonava
Jason M. Rauceo
Peter N. Lipke
Yves F. Dufrêne
author_sort Marion Mathelié-Guinlet
title Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
title_short Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
title_full Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
title_fullStr Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
title_full_unstemmed Single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
title_sort single-cell fluidic force microscopy reveals stress-dependent molecular interactions in yeast mating
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/d982771433c549ee97383aaeb1e7498c
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AT sviatlanafilimonava singlecellfluidicforcemicroscopyrevealsstressdependentmolecularinteractionsinyeastmating
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