Percolation transition of cooperative mutational effects in colorectal tumorigenesis

Cancer is caused by accumulating genetic mutations. Here, the authors investigate the cooperative effect of these mutations in colorectal cancer patients and identify a giant cluster of mutation-propagating modules that undergoes percolation transition during tumorigenesis.

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Autores principales:	Dongkwan Shin, Jonghoon Lee, Jeong-Ryeol Gong, Kwang-Hyun Cho
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d984e354889242a3bfbe10c9d2f81cab
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spelling	oai:doaj.org-article:d984e354889242a3bfbe10c9d2f81cab2021-12-02T17:06:21ZPercolation transition of cooperative mutational effects in colorectal tumorigenesis10.1038/s41467-017-01171-62041-1723https://doaj.org/article/d984e354889242a3bfbe10c9d2f81cab2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01171-6https://doaj.org/toc/2041-1723Cancer is caused by accumulating genetic mutations. Here, the authors investigate the cooperative effect of these mutations in colorectal cancer patients and identify a giant cluster of mutation-propagating modules that undergoes percolation transition during tumorigenesis.Dongkwan ShinJonghoon LeeJeong-Ryeol GongKwang-Hyun ChoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dongkwan Shin Jonghoon Lee Jeong-Ryeol Gong Kwang-Hyun Cho Percolation transition of cooperative mutational effects in colorectal tumorigenesis
description	Cancer is caused by accumulating genetic mutations. Here, the authors investigate the cooperative effect of these mutations in colorectal cancer patients and identify a giant cluster of mutation-propagating modules that undergoes percolation transition during tumorigenesis.
format	article
author	Dongkwan Shin Jonghoon Lee Jeong-Ryeol Gong Kwang-Hyun Cho
author_facet	Dongkwan Shin Jonghoon Lee Jeong-Ryeol Gong Kwang-Hyun Cho
author_sort	Dongkwan Shin
title	Percolation transition of cooperative mutational effects in colorectal tumorigenesis
title_short	Percolation transition of cooperative mutational effects in colorectal tumorigenesis
title_full	Percolation transition of cooperative mutational effects in colorectal tumorigenesis
title_fullStr	Percolation transition of cooperative mutational effects in colorectal tumorigenesis
title_full_unstemmed	Percolation transition of cooperative mutational effects in colorectal tumorigenesis
title_sort	percolation transition of cooperative mutational effects in colorectal tumorigenesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d984e354889242a3bfbe10c9d2f81cab
work_keys_str_mv	AT dongkwanshin percolationtransitionofcooperativemutationaleffectsincolorectaltumorigenesis AT jonghoonlee percolationtransitionofcooperativemutationaleffectsincolorectaltumorigenesis AT jeongryeolgong percolationtransitionofcooperativemutationaleffectsincolorectaltumorigenesis AT kwanghyuncho percolationtransitionofcooperativemutationaleffectsincolorectaltumorigenesis
_version_	1718381642069835776

Percolation transition of cooperative mutational effects in colorectal tumorigenesis

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