Oxamflatin significantly improves nuclear reprogramming, blastocyst quality, and in vitro development of bovine SCNT embryos.

Oxamflatin significantly improves nuclear reprogramming, blastocyst quality, and in vitro development of bovine SCNT embryos.

Aberrant epigenetic nuclear reprogramming results in low somatic cloning efficiency. Altering epigenetic status by applying histone deacetylase inhibitors (HDACi) enhances developmental potential of somatic cell nuclear transfer (SCNT) embryos. The present study was carried out to examine the effect...

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Autores principales: Jianmin Su, Yongsheng Wang, Yanyan Li, Ruizhe Li, Qian Li, Yongyan Wu, Fusheng Quan, Jun Liu, Zekun Guo, Yong Zhang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/d985c56a67e84a91b3183d1caad9f697
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