A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations

Transfer of scarce phosphate to organic molecules is a significant challenge for prebiotic chemistry. Here authors show a prebiotic physicochemical cycle to activate orthophosphate and via a kinetically stable, thermodynamically activated molecule phosphorylate all of life’s basic building blocks.

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Autores principales:	Oliver R. Maguire, Iris B. A. Smokers, Wilhelm T. S. Huck
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d9969f1eb84948db95a22deaf1216812
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spelling	oai:doaj.org-article:d9969f1eb84948db95a22deaf12168122021-12-02T18:02:16ZA physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations10.1038/s41467-021-25555-x2041-1723https://doaj.org/article/d9969f1eb84948db95a22deaf12168122021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25555-xhttps://doaj.org/toc/2041-1723Transfer of scarce phosphate to organic molecules is a significant challenge for prebiotic chemistry. Here authors show a prebiotic physicochemical cycle to activate orthophosphate and via a kinetically stable, thermodynamically activated molecule phosphorylate all of life’s basic building blocks.Oliver R. MaguireIris B. A. SmokersWilhelm T. S. HuckNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Oliver R. Maguire Iris B. A. Smokers Wilhelm T. S. Huck A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
description	Transfer of scarce phosphate to organic molecules is a significant challenge for prebiotic chemistry. Here authors show a prebiotic physicochemical cycle to activate orthophosphate and via a kinetically stable, thermodynamically activated molecule phosphorylate all of life’s basic building blocks.
format	article
author	Oliver R. Maguire Iris B. A. Smokers Wilhelm T. S. Huck
author_facet	Oliver R. Maguire Iris B. A. Smokers Wilhelm T. S. Huck
author_sort	Oliver R. Maguire
title	A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
title_short	A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
title_full	A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
title_fullStr	A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
title_full_unstemmed	A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
title_sort	physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d9969f1eb84948db95a22deaf1216812
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A physicochemical orthophosphate cycle via a kinetically stable thermodynamically activated intermediate enables mild prebiotic phosphorylations

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