Pathway and network analysis of more than 2500 whole cancer genomes

Understanding deregulation of biological pathways in cancer can provide insight into disease etiology and potential therapies. Here, as part of the PanCancer Analysis of Whole Genomes (PCAWG) consortium, the authors present pathway and network analysis of 2583 whole cancer genomes from 27 tumour typ...

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Autores principales:	Matthew A. Reyna, David Haan, Marta Paczkowska, Lieven P. C. Verbeke, Miguel Vazquez, Abdullah Kahraman, Sergio Pulido-Tamayo, Jonathan Barenboim, Lina Wadi, Priyanka Dhingra, Raunak Shrestha, Gad Getz, Michael S. Lawrence, Jakob Skou Pedersen, Mark A. Rubin, David A. Wheeler, Søren Brunak, Jose M. G. Izarzugaza, Ekta Khurana, Kathleen Marchal, Christian von Mering, S. Cenk Sahinalp, Alfonso Valencia, PCAWG Drivers and Functional Interpretation Working Group, Jüri Reimand, Joshua M. Stuart, Benjamin J. Raphael, PCAWG Consortium
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d9995364c8fb4afc89d4bb8a8bc2379d
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spelling	oai:doaj.org-article:d9995364c8fb4afc89d4bb8a8bc2379d2021-12-02T15:37:18ZPathway and network analysis of more than 2500 whole cancer genomes10.1038/s41467-020-14367-02041-1723https://doaj.org/article/d9995364c8fb4afc89d4bb8a8bc2379d2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14367-0https://doaj.org/toc/2041-1723Understanding deregulation of biological pathways in cancer can provide insight into disease etiology and potential therapies. Here, as part of the PanCancer Analysis of Whole Genomes (PCAWG) consortium, the authors present pathway and network analysis of 2583 whole cancer genomes from 27 tumour types.Matthew A. ReynaDavid HaanMarta PaczkowskaLieven P. C. VerbekeMiguel VazquezAbdullah KahramanSergio Pulido-TamayoJonathan BarenboimLina WadiPriyanka DhingraRaunak ShresthaGad GetzMichael S. LawrenceJakob Skou PedersenMark A. RubinDavid A. WheelerSøren BrunakJose M. G. IzarzugazaEkta KhuranaKathleen MarchalChristian von MeringS. Cenk SahinalpAlfonso ValenciaPCAWG Drivers and Functional Interpretation Working GroupJüri ReimandJoshua M. StuartBenjamin J. RaphaelPCAWG ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthew A. Reyna David Haan Marta Paczkowska Lieven P. C. Verbeke Miguel Vazquez Abdullah Kahraman Sergio Pulido-Tamayo Jonathan Barenboim Lina Wadi Priyanka Dhingra Raunak Shrestha Gad Getz Michael S. Lawrence Jakob Skou Pedersen Mark A. Rubin David A. Wheeler Søren Brunak Jose M. G. Izarzugaza Ekta Khurana Kathleen Marchal Christian von Mering S. Cenk Sahinalp Alfonso Valencia PCAWG Drivers and Functional Interpretation Working Group Jüri Reimand Joshua M. Stuart Benjamin J. Raphael PCAWG Consortium Pathway and network analysis of more than 2500 whole cancer genomes
description	Understanding deregulation of biological pathways in cancer can provide insight into disease etiology and potential therapies. Here, as part of the PanCancer Analysis of Whole Genomes (PCAWG) consortium, the authors present pathway and network analysis of 2583 whole cancer genomes from 27 tumour types.
format	article
author	Matthew A. Reyna David Haan Marta Paczkowska Lieven P. C. Verbeke Miguel Vazquez Abdullah Kahraman Sergio Pulido-Tamayo Jonathan Barenboim Lina Wadi Priyanka Dhingra Raunak Shrestha Gad Getz Michael S. Lawrence Jakob Skou Pedersen Mark A. Rubin David A. Wheeler Søren Brunak Jose M. G. Izarzugaza Ekta Khurana Kathleen Marchal Christian von Mering S. Cenk Sahinalp Alfonso Valencia PCAWG Drivers and Functional Interpretation Working Group Jüri Reimand Joshua M. Stuart Benjamin J. Raphael PCAWG Consortium
author_facet	Matthew A. Reyna David Haan Marta Paczkowska Lieven P. C. Verbeke Miguel Vazquez Abdullah Kahraman Sergio Pulido-Tamayo Jonathan Barenboim Lina Wadi Priyanka Dhingra Raunak Shrestha Gad Getz Michael S. Lawrence Jakob Skou Pedersen Mark A. Rubin David A. Wheeler Søren Brunak Jose M. G. Izarzugaza Ekta Khurana Kathleen Marchal Christian von Mering S. Cenk Sahinalp Alfonso Valencia PCAWG Drivers and Functional Interpretation Working Group Jüri Reimand Joshua M. Stuart Benjamin J. Raphael PCAWG Consortium
author_sort	Matthew A. Reyna
title	Pathway and network analysis of more than 2500 whole cancer genomes
title_short	Pathway and network analysis of more than 2500 whole cancer genomes
title_full	Pathway and network analysis of more than 2500 whole cancer genomes
title_fullStr	Pathway and network analysis of more than 2500 whole cancer genomes
title_full_unstemmed	Pathway and network analysis of more than 2500 whole cancer genomes
title_sort	pathway and network analysis of more than 2500 whole cancer genomes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d9995364c8fb4afc89d4bb8a8bc2379d
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Pathway and network analysis of more than 2500 whole cancer genomes

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