The relationship between the val158met catechol-O-methyltransferase (COMT) polymorphism and irritable bowel syndrome.

The relationship between the val158met catechol-O-methyltransferase (COMT) polymorphism and irritable bowel syndrome.

<h4>Background</h4>The catechol-O-methyltransferase (COMT) enzyme has a key function in the degradation of catecholamines and a functional polymorphism is val158met. The val/val genotype results in a three to fourfold higher enzymatic activity compared with the met/met genotype, with the...

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Autores principales: Pontus Karling, Åke Danielsson, Mikael Wikgren, Ingegerd Söderström, Jurgen Del-Favero, Rolf Adolfsson, Karl-Fredrik Norrback
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/d99ed50d3faf4050a956452da06a68fb
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