Dry eye disease ranking among common reasons for seeking eye care in a large US claims database

John L Bradley,1,2 Ipek Özer Stillman,3 Irina Pivneva,4 Annie Guerin,4 Amber M Evans,5 Reza Dana6 1Naval Medical Research Unit Dayton, Vision Science Lab, Wright Patterson AFB, OH, USA; 2University of Pikeville, Kentucky College of Optometry, Pikeville, KY, USA; 3Takeda, Lexington, MA, USA...

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Autores principales:	Bradley JL, Özer Stillman I, Pivneva I, Guerin A, Evans AM, Dana R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	DED epidemiology prevalence incidence Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/d9a055814c504141aa21ea84aebf23d2
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spelling	oai:doaj.org-article:d9a055814c504141aa21ea84aebf23d22021-12-02T05:53:46ZDry eye disease ranking among common reasons for seeking eye care in a large US claims database1177-5483https://doaj.org/article/d9a055814c504141aa21ea84aebf23d22019-02-01T00:00:00Zhttps://www.dovepress.com/dry-eye-disease-ranking-among-common-reasons-for-seeking-eye-care-in-a-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483John L Bradley,1,2 Ipek Özer Stillman,3 Irina Pivneva,4 Annie Guerin,4 Amber M Evans,5 Reza Dana6 1Naval Medical Research Unit Dayton, Vision Science Lab, Wright Patterson AFB, OH, USA; 2University of Pikeville, Kentucky College of Optometry, Pikeville, KY, USA; 3Takeda, Lexington, MA, USA; 4Analysis Group, Inc, Montreal, QC, Canada; 5Health ResearchTx LLC, Trevose, PA, USA; 6Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA Objectives: Dry eye disease (DED) is a complex multifactorial condition of the ocular surface characterized by symptoms of ocular discomfort, irritation, and visual disturbance. Data previously reported from this study showed an increase in prevalence and incidence of DED with age and over time. The objective of this study was to compare the ranking of DED prevalence among other ocular conditions that led patients to seek eye care. Methods: In this population-based study using the US Department of Defense Military Health System claims database of >9.7 million beneficiaries, indicators of DED and other ocular conditions were analyzed over time. The overall prevalence (2003–2015) and annual incidence (2008–2012) of DED and other ocular conditions were estimated using an algorithm based on two independent indicators derived from selected diagnostic and procedure codes and prescriptions for cyclosporine ophthalmic emulsion for DED and diagnostic codes for the indicators of other common ocular conditions. Results: In 2003–2015, the most common ocular conditions were disorders of refraction and accommodation (25.84%), cataracts (17.14%), glaucoma (7.27%), disorders of the conjunctiva (6.76%), other retinal disorders (5.94%), and DED (5.28%). DED was the fifth most prevalent ocular condition in women (7.78%) and ninth most prevalent in men (2.96%). In 2012, DED had the third highest annual incidence (0.87%), behind disorders of refraction/accommodation (1.87%) and cataracts (1.50%). Conclusion: This study provided further epidemiologic evidence for DED as a commonly occurring condition that drives patients to seek treatment. Keywords: DED, epidemiology, prevalence, incidenceBradley JLÖzer Stillman IPivneva IGuerin AEvans AMDana RDove Medical PressarticleDEDepidemiologyprevalenceincidenceOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 225-232 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	DED epidemiology prevalence incidence Ophthalmology RE1-994
spellingShingle	DED epidemiology prevalence incidence Ophthalmology RE1-994 Bradley JL Özer Stillman I Pivneva I Guerin A Evans AM Dana R Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
description	John L Bradley,1,2 Ipek Özer Stillman,3 Irina Pivneva,4 Annie Guerin,4 Amber M Evans,5 Reza Dana6 1Naval Medical Research Unit Dayton, Vision Science Lab, Wright Patterson AFB, OH, USA; 2University of Pikeville, Kentucky College of Optometry, Pikeville, KY, USA; 3Takeda, Lexington, MA, USA; 4Analysis Group, Inc, Montreal, QC, Canada; 5Health ResearchTx LLC, Trevose, PA, USA; 6Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA Objectives: Dry eye disease (DED) is a complex multifactorial condition of the ocular surface characterized by symptoms of ocular discomfort, irritation, and visual disturbance. Data previously reported from this study showed an increase in prevalence and incidence of DED with age and over time. The objective of this study was to compare the ranking of DED prevalence among other ocular conditions that led patients to seek eye care. Methods: In this population-based study using the US Department of Defense Military Health System claims database of >9.7 million beneficiaries, indicators of DED and other ocular conditions were analyzed over time. The overall prevalence (2003–2015) and annual incidence (2008–2012) of DED and other ocular conditions were estimated using an algorithm based on two independent indicators derived from selected diagnostic and procedure codes and prescriptions for cyclosporine ophthalmic emulsion for DED and diagnostic codes for the indicators of other common ocular conditions. Results: In 2003–2015, the most common ocular conditions were disorders of refraction and accommodation (25.84%), cataracts (17.14%), glaucoma (7.27%), disorders of the conjunctiva (6.76%), other retinal disorders (5.94%), and DED (5.28%). DED was the fifth most prevalent ocular condition in women (7.78%) and ninth most prevalent in men (2.96%). In 2012, DED had the third highest annual incidence (0.87%), behind disorders of refraction/accommodation (1.87%) and cataracts (1.50%). Conclusion: This study provided further epidemiologic evidence for DED as a commonly occurring condition that drives patients to seek treatment. Keywords: DED, epidemiology, prevalence, incidence
format	article
author	Bradley JL Özer Stillman I Pivneva I Guerin A Evans AM Dana R
author_facet	Bradley JL Özer Stillman I Pivneva I Guerin A Evans AM Dana R
author_sort	Bradley JL
title	Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
title_short	Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
title_full	Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
title_fullStr	Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
title_full_unstemmed	Dry eye disease ranking among common reasons for seeking eye care in a large US claims database
title_sort	dry eye disease ranking among common reasons for seeking eye care in a large us claims database
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/d9a055814c504141aa21ea84aebf23d2
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Dry eye disease ranking among common reasons for seeking eye care in a large US claims database

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