Serum Erythropoietin level in children with different degrees of chronic renal failure

Objective: Kidneys are major sites of erythropoietin production and in chronic renal failure (CRF), erythropoietin production decreases and leads to anemia. This study was done in children with different degrees of CRF and with primary disease of tubules and glomeruli. Methods: In this study 45 chil...

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Autores principales:	Gh Al-Hosseini Hashemi, H Sorkhi, A Ghaderi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2000
Materias:	chronic renal failure erythropoietin anemia children Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d9a44f87d0dc4bd59e31641bc4394038
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spelling	oai:doaj.org-article:d9a44f87d0dc4bd59e31641bc43940382021-11-10T09:22:21ZSerum Erythropoietin level in children with different degrees of chronic renal failure1561-41072251-7170https://doaj.org/article/d9a44f87d0dc4bd59e31641bc43940382000-10-01T00:00:00Zhttp://jbums.org/article-1-2895-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Kidneys are major sites of erythropoietin production and in chronic renal failure (CRF), erythropoietin production decreases and leads to anemia. This study was done in children with different degrees of CRF and with primary disease of tubules and glomeruli. Methods: In this study 45 children with CRF and glomerular filtration rate, less than 50ml per minute for 1.73 m2 of body surface were divided into moderate, severe and end stage renal disease (ESRD). Serum hemoglobin and erythropoietin levels were evaluated with severity of CRF. Findings: The mean of serum erythropoietin level in normal group was 10.9 mlu/ml and in moderate, severe and ESRD were 13.5, 9.7 and 9.1 mlu/ml respectively. Erythropoietin level in primary tubular disease were 13.9, 13.6 and 10.5 mlu/ml and in glomerular disease were 12.75, 7 and 7.5 mlu/ml. Conclusion: The comparison of hemoglobin and erythropoietin in these group shows that the less the renal function, the more severe the anemia and there was not a significant difference in the level of serum erythropoietin in tubular or glomerular disease.Gh Al-Hosseini HashemiH SorkhiA GhaderiBabol University of Medical Sciencesarticlechronic renal failureerythropoietinanemiachildrenMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 2, Iss 4, Pp 46-50 (2000)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	chronic renal failure erythropoietin anemia children Medicine R Medicine (General) R5-920
spellingShingle	chronic renal failure erythropoietin anemia children Medicine R Medicine (General) R5-920 Gh Al-Hosseini Hashemi H Sorkhi A Ghaderi Serum Erythropoietin level in children with different degrees of chronic renal failure
description	Objective: Kidneys are major sites of erythropoietin production and in chronic renal failure (CRF), erythropoietin production decreases and leads to anemia. This study was done in children with different degrees of CRF and with primary disease of tubules and glomeruli. Methods: In this study 45 children with CRF and glomerular filtration rate, less than 50ml per minute for 1.73 m2 of body surface were divided into moderate, severe and end stage renal disease (ESRD). Serum hemoglobin and erythropoietin levels were evaluated with severity of CRF. Findings: The mean of serum erythropoietin level in normal group was 10.9 mlu/ml and in moderate, severe and ESRD were 13.5, 9.7 and 9.1 mlu/ml respectively. Erythropoietin level in primary tubular disease were 13.9, 13.6 and 10.5 mlu/ml and in glomerular disease were 12.75, 7 and 7.5 mlu/ml. Conclusion: The comparison of hemoglobin and erythropoietin in these group shows that the less the renal function, the more severe the anemia and there was not a significant difference in the level of serum erythropoietin in tubular or glomerular disease.
format	article
author	Gh Al-Hosseini Hashemi H Sorkhi A Ghaderi
author_facet	Gh Al-Hosseini Hashemi H Sorkhi A Ghaderi
author_sort	Gh Al-Hosseini Hashemi
title	Serum Erythropoietin level in children with different degrees of chronic renal failure
title_short	Serum Erythropoietin level in children with different degrees of chronic renal failure
title_full	Serum Erythropoietin level in children with different degrees of chronic renal failure
title_fullStr	Serum Erythropoietin level in children with different degrees of chronic renal failure
title_full_unstemmed	Serum Erythropoietin level in children with different degrees of chronic renal failure
title_sort	serum erythropoietin level in children with different degrees of chronic renal failure
publisher	Babol University of Medical Sciences
publishDate	2000
url	https://doaj.org/article/d9a44f87d0dc4bd59e31641bc4394038
work_keys_str_mv	AT ghalhosseinihashemi serumerythropoietinlevelinchildrenwithdifferentdegreesofchronicrenalfailure AT hsorkhi serumerythropoietinlevelinchildrenwithdifferentdegreesofchronicrenalfailure AT aghaderi serumerythropoietinlevelinchildrenwithdifferentdegreesofchronicrenalfailure
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Serum Erythropoietin level in children with different degrees of chronic renal failure

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