Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene

Abstract Here we report an in-silico approach for identification, characterization and validation of deleterious non-synonymous SNPs (nsSNPs) in the interleukin-8 gene using three steps. In first step, sequence homology-based genetic analysis of a set of 50 coding SNPs associated with 41 rsIDs using...

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Autores principales: Tikam Chand Dakal, Deepak Kala, Gourav Dhiman, Vinod Yadav, Andrey Krokhotin, Nikolay V. Dokholyan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d9a6375912c24d70811c11d176d6384b
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