Enzyme-mimetic self-catalyzed polymerization of polypeptide helices
The folding-dependent catalytic behavior of enzymes is of fundamental biological importance, yet mechanistically underexplored. Here, the authors show that an α-helix, commonly found in proteins, can facilitate its own growth through the self-catalyzed polymerization of N-carboxyanhydride in solvent...
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Main Authors: | Ziyuan Song, Hailin Fu, Ryan Baumgartner, Lingyang Zhu, Kuo-Chih Shih, Yingchun Xia, Xuetao Zheng, Lichen Yin, Christophe Chipot, Yao Lin, Jianjun Cheng |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/d9c8265f36f1439fbf9f3949a2e2ae98 |
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