Enzyme-mimetic self-catalyzed polymerization of polypeptide helices

The folding-dependent catalytic behavior of enzymes is of fundamental biological importance, yet mechanistically underexplored. Here, the authors show that an α-helix, commonly found in proteins, can facilitate its own growth through the self-catalyzed polymerization of N-carboxyanhydride in solvent...

Full description

Saved in:
Bibliographic Details
Main Authors: Ziyuan Song, Hailin Fu, Ryan Baumgartner, Lingyang Zhu, Kuo-Chih Shih, Yingchun Xia, Xuetao Zheng, Lichen Yin, Christophe Chipot, Yao Lin, Jianjun Cheng
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/d9c8265f36f1439fbf9f3949a2e2ae98
Tags: Add Tag
No Tags, Be the first to tag this record!