Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey

Background and Aim: Marek's disease (MD) is a lymphoproliferative disease that occurs in chickens. In the absence of control measures, MD causes devastating losses to commercial poultry flocks. Vaccination has enabled dramatic success in the prevention and control of MD. However, the MD vaccina...

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Autores principales:	Lounas Abdelaziz, Besbaci Mohamed, Akkou Madjid, Tali Oumennoune
Formato:	article
Lenguaje:	EN
Publicado:	Veterinary World 2021
Materias:	algeria broiler breeder flocks histopathological findings marek's disease tumors Animal culture SF1-1100 Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/d9d6bd871ffd42949e03a1a75909bb5a
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spelling	oai:doaj.org-article:d9d6bd871ffd42949e03a1a75909bb5a2021-11-28T15:17:00ZOccurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey10.14202/vetworld.2021.3021-30270972-89882231-0916https://doaj.org/article/d9d6bd871ffd42949e03a1a75909bb5a2021-11-01T00:00:00Zhttp://www.veterinaryworld.org/Vol.14/November-2021/24.pdfhttps://doaj.org/toc/0972-8988https://doaj.org/toc/2231-0916Background and Aim: Marek's disease (MD) is a lymphoproliferative disease that occurs in chickens. In the absence of control measures, MD causes devastating losses to commercial poultry flocks. Vaccination has enabled dramatic success in the prevention and control of MD. However, the MD vaccination program has failed frequently, and occasional clinical outbreaks have been reported in the vaccinated flocks as well. The present study aimed to describe the clinical and histopathological characteristics of the field cases of MD in broiler breeder flocks. Materials and Methods: A survey on the update of MD occurrence in Algerian broiler breeder flocks was conducted from June 2020 to September 2020. Ten vaccinated broiler breeder flocks located in Central Algeria and having progressive tumors in different visceral organs were evaluated for MD virus infection by conducting a histopathological examination of the birds. Results: The age of the birds affected with MD ranged from 13 to 22 weeks. The mortality rate varied sensitively from 4% to 10%. The clinical symptoms reported in the affected flocks included locomotor, nervous, digestive, and respiratory symptoms. Necropsy of the dead or euthanized birds revealed visceral lymphomatosis in several organs and macroscopic changes in the peripheral nerves (including loss of longitudinal striation, color change [grayish], and volume increase). The histopathological findings included the infiltration and proliferation of lymphocytes and blast cells (lymphoblasts) in various organs of the birds, which are the typical characteristics of MD and, therefore, confirmed the field infection of MD in these birds. Conclusion: The present study provided evidence for the high prevalence of MD in the broiler breeder flocks vaccinated with a bivalent vaccine (turkey herpesvirus+Rispens) at the hatchery. The findings of the present study may indicate highlevel failure of vaccination in these birds.Lounas AbdelazizBesbaci MohamedAkkou MadjidTali OumennouneVeterinary Worldarticlealgeriabroiler breeder flockshistopathological findingsmarek's diseasetumorsAnimal cultureSF1-1100Veterinary medicineSF600-1100ENVeterinary World, Vol 14, Iss 11, Pp 3021-3027 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	algeria broiler breeder flocks histopathological findings marek's disease tumors Animal culture SF1-1100 Veterinary medicine SF600-1100
spellingShingle	algeria broiler breeder flocks histopathological findings marek's disease tumors Animal culture SF1-1100 Veterinary medicine SF600-1100 Lounas Abdelaziz Besbaci Mohamed Akkou Madjid Tali Oumennoune Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
description	Background and Aim: Marek's disease (MD) is a lymphoproliferative disease that occurs in chickens. In the absence of control measures, MD causes devastating losses to commercial poultry flocks. Vaccination has enabled dramatic success in the prevention and control of MD. However, the MD vaccination program has failed frequently, and occasional clinical outbreaks have been reported in the vaccinated flocks as well. The present study aimed to describe the clinical and histopathological characteristics of the field cases of MD in broiler breeder flocks. Materials and Methods: A survey on the update of MD occurrence in Algerian broiler breeder flocks was conducted from June 2020 to September 2020. Ten vaccinated broiler breeder flocks located in Central Algeria and having progressive tumors in different visceral organs were evaluated for MD virus infection by conducting a histopathological examination of the birds. Results: The age of the birds affected with MD ranged from 13 to 22 weeks. The mortality rate varied sensitively from 4% to 10%. The clinical symptoms reported in the affected flocks included locomotor, nervous, digestive, and respiratory symptoms. Necropsy of the dead or euthanized birds revealed visceral lymphomatosis in several organs and macroscopic changes in the peripheral nerves (including loss of longitudinal striation, color change [grayish], and volume increase). The histopathological findings included the infiltration and proliferation of lymphocytes and blast cells (lymphoblasts) in various organs of the birds, which are the typical characteristics of MD and, therefore, confirmed the field infection of MD in these birds. Conclusion: The present study provided evidence for the high prevalence of MD in the broiler breeder flocks vaccinated with a bivalent vaccine (turkey herpesvirus+Rispens) at the hatchery. The findings of the present study may indicate highlevel failure of vaccination in these birds.
format	article
author	Lounas Abdelaziz Besbaci Mohamed Akkou Madjid Tali Oumennoune
author_facet	Lounas Abdelaziz Besbaci Mohamed Akkou Madjid Tali Oumennoune
author_sort	Lounas Abdelaziz
title	Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
title_short	Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
title_full	Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
title_fullStr	Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
title_full_unstemmed	Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey
title_sort	occurrence of marek's disease in vaccinated algerian broiler breeder flocks: a histopathological survey
publisher	Veterinary World
publishDate	2021
url	https://doaj.org/article/d9d6bd871ffd42949e03a1a75909bb5a
work_keys_str_mv	AT lounasabdelaziz occurrenceofmareksdiseaseinvaccinatedalgerianbroilerbreederflocksahistopathologicalsurvey AT besbacimohamed occurrenceofmareksdiseaseinvaccinatedalgerianbroilerbreederflocksahistopathologicalsurvey AT akkoumadjid occurrenceofmareksdiseaseinvaccinatedalgerianbroilerbreederflocksahistopathologicalsurvey AT talioumennoune occurrenceofmareksdiseaseinvaccinatedalgerianbroilerbreederflocksahistopathologicalsurvey
_version_	1718407861344665600

Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey

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