Emerging nanotechnology approaches in tissue engineering and regenerative medicine

Eung-Sam Kim,1,2 Eun Hyun Ahn,3,4 Tal Dvir,5,6 Deok-Ho Kim1,4,71Department of Bioengineering, University of Washington, Seattle, WA, USA; 2Department of Biological Sciences, Chonnam National University, Gwangju, Korea; 3Department of Pathology, 4Institute of Stem Cell and Regenerative Medicine, Sch...

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Autores principales:	Kim ES, Ahn EH, Dvir T, Kim DH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d9ddf5d262e94fbe8cbd8dee0ee8984d
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spelling	oai:doaj.org-article:d9ddf5d262e94fbe8cbd8dee0ee8984d2021-12-02T05:40:37ZEmerging nanotechnology approaches in tissue engineering and regenerative medicine1178-2013https://doaj.org/article/d9ddf5d262e94fbe8cbd8dee0ee8984d2014-05-01T00:00:00Zhttp://www.dovepress.com/emerging-nanotechnology-approaches-in-tissue-engineering-and-regenerat-a16691https://doaj.org/toc/1178-2013 Eung-Sam Kim,1,2 Eun Hyun Ahn,3,4 Tal Dvir,5,6 Deok-Ho Kim1,4,71Department of Bioengineering, University of Washington, Seattle, WA, USA; 2Department of Biological Sciences, Chonnam National University, Gwangju, Korea; 3Department of Pathology, 4Institute of Stem Cell and Regenerative Medicine, School of Medicine, University of Washington, Seattle, WA, USA; 5Department of Molecular Microbiology and Biotechnology, 6Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel; 7Center for Cardiovascular Biology, University of Washington, Seattle, WA, USAThe history of human kind suggests that there has been a correlation between global population growth and major events in science and technology over the last three centuries. Sharp increases in the world’s population have been triggered by the industrial revolution and scientific and technological breakthroughs including: the advent of the railways, discovery of penicillin and deoxyribonucleic acid (DNA), and the invention of the computer.1 Since the 20th century, interdisciplinary areas in the physical and biological sciences have accelerated the progress of biomedical applications. The recent integration of emerging nanotechnology into biology and biomedicine has resulted in a range of innovative nanoengineering efforts for the repair and regeneration of tissues and organs.2 Thus, it is expected that nanoengineering approaches to biomedical applications can contribute to addressing the present issue of personal and global health care and its economic burden for more than 7 billion people.Why are we paying attention to nanoengineering for biomedical applications? The size of most biomolecules ranges from 0.2 nm to 200 nm (Figure 1). Research has focused on control of the interaction and localization of biomolecules even at the single-molecule level using ever-evolving nanotechnology.3 The evidence indicates that cells can respond to nanoscale changes in the dynamic extracellular matrix and vice versa. Biomimetic nanopatterns alone can direct the differentiation of stem cells without involvement of exogenous soluble biochemical factors.4,5 This regulation of cellular behavior by nanotechnology is one of many examples demonstrating the significant applications of nanoengineering in biomedicine. This special issue includes four review papers and seven research articles that provide an insight into current nanoengineering approaches to the repair or regeneration of tissues and organs.Kim ESAhn EHDvir TKim DHDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Supplement 1, Pp 1-5 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Kim ES Ahn EH Dvir T Kim DH Emerging nanotechnology approaches in tissue engineering and regenerative medicine
description	Eung-Sam Kim,1,2 Eun Hyun Ahn,3,4 Tal Dvir,5,6 Deok-Ho Kim1,4,71Department of Bioengineering, University of Washington, Seattle, WA, USA; 2Department of Biological Sciences, Chonnam National University, Gwangju, Korea; 3Department of Pathology, 4Institute of Stem Cell and Regenerative Medicine, School of Medicine, University of Washington, Seattle, WA, USA; 5Department of Molecular Microbiology and Biotechnology, 6Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel; 7Center for Cardiovascular Biology, University of Washington, Seattle, WA, USAThe history of human kind suggests that there has been a correlation between global population growth and major events in science and technology over the last three centuries. Sharp increases in the world’s population have been triggered by the industrial revolution and scientific and technological breakthroughs including: the advent of the railways, discovery of penicillin and deoxyribonucleic acid (DNA), and the invention of the computer.1 Since the 20th century, interdisciplinary areas in the physical and biological sciences have accelerated the progress of biomedical applications. The recent integration of emerging nanotechnology into biology and biomedicine has resulted in a range of innovative nanoengineering efforts for the repair and regeneration of tissues and organs.2 Thus, it is expected that nanoengineering approaches to biomedical applications can contribute to addressing the present issue of personal and global health care and its economic burden for more than 7 billion people.Why are we paying attention to nanoengineering for biomedical applications? The size of most biomolecules ranges from 0.2 nm to 200 nm (Figure 1). Research has focused on control of the interaction and localization of biomolecules even at the single-molecule level using ever-evolving nanotechnology.3 The evidence indicates that cells can respond to nanoscale changes in the dynamic extracellular matrix and vice versa. Biomimetic nanopatterns alone can direct the differentiation of stem cells without involvement of exogenous soluble biochemical factors.4,5 This regulation of cellular behavior by nanotechnology is one of many examples demonstrating the significant applications of nanoengineering in biomedicine. This special issue includes four review papers and seven research articles that provide an insight into current nanoengineering approaches to the repair or regeneration of tissues and organs.
format	article
author	Kim ES Ahn EH Dvir T Kim DH
author_facet	Kim ES Ahn EH Dvir T Kim DH
author_sort	Kim ES
title	Emerging nanotechnology approaches in tissue engineering and regenerative medicine
title_short	Emerging nanotechnology approaches in tissue engineering and regenerative medicine
title_full	Emerging nanotechnology approaches in tissue engineering and regenerative medicine
title_fullStr	Emerging nanotechnology approaches in tissue engineering and regenerative medicine
title_full_unstemmed	Emerging nanotechnology approaches in tissue engineering and regenerative medicine
title_sort	emerging nanotechnology approaches in tissue engineering and regenerative medicine
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/d9ddf5d262e94fbe8cbd8dee0ee8984d
work_keys_str_mv	AT kimes emergingnanotechnologyapproachesintissueengineeringandregenerativemedicine AT ahneh emergingnanotechnologyapproachesintissueengineeringandregenerativemedicine AT dvirt emergingnanotechnologyapproachesintissueengineeringandregenerativemedicine AT kimdh emergingnanotechnologyapproachesintissueengineeringandregenerativemedicine
_version_	1718400324262166528

Emerging nanotechnology approaches in tissue engineering and regenerative medicine

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