Sources, propagation and consequences of stochasticity in cellular growth

The drivers of growth rate variability in bacteria are yet unknown. Here, the authors present a theory to predict the growth dynamics of individual cells and use a stochastic cell model integrating metabolism, gene expression and replication to identify the processes that underlie growth variation.

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Autores principales: Philipp Thomas, Guillaume Terradot, Vincent Danos, Andrea Y. Weiße
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d9e082eab9714756b14cf784f6488905
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spelling oai:doaj.org-article:d9e082eab9714756b14cf784f64889052021-12-02T17:31:45ZSources, propagation and consequences of stochasticity in cellular growth10.1038/s41467-018-06912-92041-1723https://doaj.org/article/d9e082eab9714756b14cf784f64889052018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06912-9https://doaj.org/toc/2041-1723The drivers of growth rate variability in bacteria are yet unknown. Here, the authors present a theory to predict the growth dynamics of individual cells and use a stochastic cell model integrating metabolism, gene expression and replication to identify the processes that underlie growth variation.Philipp ThomasGuillaume TerradotVincent DanosAndrea Y. WeißeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Philipp Thomas
Guillaume Terradot
Vincent Danos
Andrea Y. Weiße
Sources, propagation and consequences of stochasticity in cellular growth
description The drivers of growth rate variability in bacteria are yet unknown. Here, the authors present a theory to predict the growth dynamics of individual cells and use a stochastic cell model integrating metabolism, gene expression and replication to identify the processes that underlie growth variation.
format article
author Philipp Thomas
Guillaume Terradot
Vincent Danos
Andrea Y. Weiße
author_facet Philipp Thomas
Guillaume Terradot
Vincent Danos
Andrea Y. Weiße
author_sort Philipp Thomas
title Sources, propagation and consequences of stochasticity in cellular growth
title_short Sources, propagation and consequences of stochasticity in cellular growth
title_full Sources, propagation and consequences of stochasticity in cellular growth
title_fullStr Sources, propagation and consequences of stochasticity in cellular growth
title_full_unstemmed Sources, propagation and consequences of stochasticity in cellular growth
title_sort sources, propagation and consequences of stochasticity in cellular growth
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d9e082eab9714756b14cf784f6488905
work_keys_str_mv AT philippthomas sourcespropagationandconsequencesofstochasticityincellulargrowth
AT guillaumeterradot sourcespropagationandconsequencesofstochasticityincellulargrowth
AT vincentdanos sourcespropagationandconsequencesofstochasticityincellulargrowth
AT andreayweiße sourcespropagationandconsequencesofstochasticityincellulargrowth
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