MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS

Abstract. Mycobacteriosis is an infectious disease of animals and humans caused by non-tuberculosis mycobacteria including M. avium complex. Despite the fact that the transmission of M. avium from human to human has not been proved, and mycobacteriosis has been sporadic, the number of cases of disse...

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Autor principal:	D. A. Starkova
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	mycobacteriosis mycobacterium avium genotyping Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/d9ed8dc826b447aa92c32afdbe3028e0
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spelling	oai:doaj.org-article:d9ed8dc826b447aa92c32afdbe3028e02021-11-22T07:09:46ZMYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS2220-76192313-739810.15789/2220-7619-2013-1-7-14https://doaj.org/article/d9ed8dc826b447aa92c32afdbe3028e02014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/117https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. Mycobacteriosis is an infectious disease of animals and humans caused by non-tuberculosis mycobacteria including M. avium complex. Despite the fact that the transmission of M. avium from human to human has not been proved, and mycobacteriosis has been sporadic, the number of cases of disseminated forms of disease caused by M. avium among HIV-positive patients during the last ten years was increasing. Limited knowledge about the structure of M. avium population in Russia and the lack of simple methods for the microbiological diagnosis make difficult the epidemiological monitoring of mycobacteriosis. This facilitates the use of modern, efficient molecular genetic methods for the species and subspecies identification and typing of M. avium. Thus, the detection of mobile element IS901, restriction fragment polymorphism analysis of hsp65 gene and IS1245 allow the detection and subspecies identification of M. avium. The study of genomic polymorphisms of bacterial strains for the assessment of M. avium population structure became feasible due to a complex of molecular techniques: VNTR-typing, IS1245-and IS1311-RFLP-typing.D. A. StarkovaSankt-Peterburg : NIIÈM imeni Pasteraarticlemycobacteriosismycobacterium aviumgenotypingInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 1, Pp 7-14 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	mycobacteriosis mycobacterium avium genotyping Infectious and parasitic diseases RC109-216
spellingShingle	mycobacteriosis mycobacterium avium genotyping Infectious and parasitic diseases RC109-216 D. A. Starkova MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
description	Abstract. Mycobacteriosis is an infectious disease of animals and humans caused by non-tuberculosis mycobacteria including M. avium complex. Despite the fact that the transmission of M. avium from human to human has not been proved, and mycobacteriosis has been sporadic, the number of cases of disseminated forms of disease caused by M. avium among HIV-positive patients during the last ten years was increasing. Limited knowledge about the structure of M. avium population in Russia and the lack of simple methods for the microbiological diagnosis make difficult the epidemiological monitoring of mycobacteriosis. This facilitates the use of modern, efficient molecular genetic methods for the species and subspecies identification and typing of M. avium. Thus, the detection of mobile element IS901, restriction fragment polymorphism analysis of hsp65 gene and IS1245 allow the detection and subspecies identification of M. avium. The study of genomic polymorphisms of bacterial strains for the assessment of M. avium population structure became feasible due to a complex of molecular techniques: VNTR-typing, IS1245-and IS1311-RFLP-typing.
format	article
author	D. A. Starkova
author_facet	D. A. Starkova
author_sort	D. A. Starkova
title	MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
title_short	MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
title_full	MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
title_fullStr	MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
title_full_unstemmed	MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS
title_sort	mycobacterium avium as an actual pathogen of human mycobacteriosis
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/d9ed8dc826b447aa92c32afdbe3028e0
work_keys_str_mv	AT dastarkova mycobacteriumaviumasanactualpathogenofhumanmycobacteriosis
_version_	1718418073205080064

MYCOBACTERIUM AVIUM AS AN ACTUAL PATHOGEN OF HUMAN MYCOBACTERIOSIS

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