Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice.

Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice.

The "mechanistic target of rapamycin" (mTOR) is a central controller of growth, proliferation and/or motility of various cell-types ranging from adipocytes to immune cells, thereby linking metabolism and immunity. mTOR signaling is overactivated in obesity, promoting inflammation and insul...

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Autores principales: Kassem Makki, Solenne Taront, Olivier Molendi-Coste, Emmanuel Bouchaert, Bernadette Neve, Elodie Eury, Stéphane Lobbens, Myriam Labalette, Hélène Duez, Bart Staels, David Dombrowicz, Philippe Froguel, Isabelle Wolowczuk
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d9f98ed9519749d696812e9679e5562a
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