Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)

The crosstalk between gut microbiota and host immunity has emerged as one of the research foci of microbiome studies in recent years. The purpose of this study was to determine how gut microbes respond to fungal infection in termites, given their reliance on gut symbionts for food intake as well as...

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Autores principales:	Chen-Yu Wu, Jing Meng, Austin Merchant, Yi-Xiang Zhang, Mu-Wang Li, Xu-Guo Zhou, Qian Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	Odontotermes formosanus Metarhizium robertsii 16S rDNA sequencing metagenome gut microbiota Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/d9fbce04f99c46f8a936f4cdd0886a70
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spelling	oai:doaj.org-article:d9fbce04f99c46f8a936f4cdd0886a702021-11-22T06:16:34ZMicrobial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)1664-302X10.3389/fmicb.2021.723508https://doaj.org/article/d9fbce04f99c46f8a936f4cdd0886a702021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmicb.2021.723508/fullhttps://doaj.org/toc/1664-302XThe crosstalk between gut microbiota and host immunity has emerged as one of the research foci of microbiome studies in recent years. The purpose of this study was to determine how gut microbes respond to fungal infection in termites, given their reliance on gut symbionts for food intake as well as maintaining host health. Here, we used Metarhizium robertsii, an entomopathogenic fungus, to infect Odontotermes formosanus, a fungus-growing termite in the family Termitidae, and documented changes in host gut microbiota via a combination of bacterial 16S rDNA sequencing, metagenomic shotgun sequencing, and transmission electron microscopy. Our analyses found that when challenged with Metarhizium, the termite gut showed reduced microbial diversity within the first 12 h of fungal infection and then recovered and even surpassed pre-infection flora levels. These combined results shed light on the role of gut flora in maintaining homeostasis and immune homeostasis in the host, and the impact of gut flora dysbiosis on host susceptibility to infection.Chen-Yu WuChen-Yu WuJing MengAustin MerchantYi-Xiang ZhangYi-Xiang ZhangMu-Wang LiXu-Guo ZhouQian WangFrontiers Media S.A.articleOdontotermes formosanusMetarhizium robertsii16S rDNA sequencingmetagenomegut microbiotaMicrobiologyQR1-502ENFrontiers in Microbiology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Odontotermes formosanus Metarhizium robertsii 16S rDNA sequencing metagenome gut microbiota Microbiology QR1-502
spellingShingle	Odontotermes formosanus Metarhizium robertsii 16S rDNA sequencing metagenome gut microbiota Microbiology QR1-502 Chen-Yu Wu Chen-Yu Wu Jing Meng Austin Merchant Yi-Xiang Zhang Yi-Xiang Zhang Mu-Wang Li Xu-Guo Zhou Qian Wang Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
description	The crosstalk between gut microbiota and host immunity has emerged as one of the research foci of microbiome studies in recent years. The purpose of this study was to determine how gut microbes respond to fungal infection in termites, given their reliance on gut symbionts for food intake as well as maintaining host health. Here, we used Metarhizium robertsii, an entomopathogenic fungus, to infect Odontotermes formosanus, a fungus-growing termite in the family Termitidae, and documented changes in host gut microbiota via a combination of bacterial 16S rDNA sequencing, metagenomic shotgun sequencing, and transmission electron microscopy. Our analyses found that when challenged with Metarhizium, the termite gut showed reduced microbial diversity within the first 12 h of fungal infection and then recovered and even surpassed pre-infection flora levels. These combined results shed light on the role of gut flora in maintaining homeostasis and immune homeostasis in the host, and the impact of gut flora dysbiosis on host susceptibility to infection.
format	article
author	Chen-Yu Wu Chen-Yu Wu Jing Meng Austin Merchant Yi-Xiang Zhang Yi-Xiang Zhang Mu-Wang Li Xu-Guo Zhou Qian Wang
author_facet	Chen-Yu Wu Chen-Yu Wu Jing Meng Austin Merchant Yi-Xiang Zhang Yi-Xiang Zhang Mu-Wang Li Xu-Guo Zhou Qian Wang
author_sort	Chen-Yu Wu
title	Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
title_short	Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
title_full	Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
title_fullStr	Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
title_full_unstemmed	Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)
title_sort	microbial response to fungal infection in a fungus-growing termite, odontotermes formosanus (shiraki)
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/d9fbce04f99c46f8a936f4cdd0886a70
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Microbial Response to Fungal Infection in a Fungus-Growing Termite, Odontotermes formosanus (Shiraki)

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