A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats

Animals constantly balance seeking food with avoiding predators. Here, the authors report that CRF positive neurons in the paraventricular thalamus projecting to the nucleus accumbens in rats are an indispensable component of a feedback circuit that can interrupt appetitive behaviour in favor of a d...

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Autores principales:	D. S. Engelke, X. O. Zhang, J. J. O’Malley, J. A. Fernandez-Leon, S. Li, G. J. Kirouac, M. Beierlein, F. H. Do-Monte
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/da0fbb3253a641e9a1dab25e6c597513
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spelling	oai:doaj.org-article:da0fbb3253a641e9a1dab25e6c5975132021-12-02T15:38:20ZA hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats10.1038/s41467-021-22730-y2041-1723https://doaj.org/article/da0fbb3253a641e9a1dab25e6c5975132021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22730-yhttps://doaj.org/toc/2041-1723Animals constantly balance seeking food with avoiding predators. Here, the authors report that CRF positive neurons in the paraventricular thalamus projecting to the nucleus accumbens in rats are an indispensable component of a feedback circuit that can interrupt appetitive behaviour in favor of a defensive response in the presence of a competing threat stimulus.D. S. EngelkeX. O. ZhangJ. J. O’MalleyJ. A. Fernandez-LeonS. LiG. J. KirouacM. BeierleinF. H. Do-MonteNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q D. S. Engelke X. O. Zhang J. J. O’Malley J. A. Fernandez-Leon S. Li G. J. Kirouac M. Beierlein F. H. Do-Monte A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
description	Animals constantly balance seeking food with avoiding predators. Here, the authors report that CRF positive neurons in the paraventricular thalamus projecting to the nucleus accumbens in rats are an indispensable component of a feedback circuit that can interrupt appetitive behaviour in favor of a defensive response in the presence of a competing threat stimulus.
format	article
author	D. S. Engelke X. O. Zhang J. J. O’Malley J. A. Fernandez-Leon S. Li G. J. Kirouac M. Beierlein F. H. Do-Monte
author_facet	D. S. Engelke X. O. Zhang J. J. O’Malley J. A. Fernandez-Leon S. Li G. J. Kirouac M. Beierlein F. H. Do-Monte
author_sort	D. S. Engelke
title	A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
title_short	A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
title_full	A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
title_fullStr	A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
title_full_unstemmed	A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
title_sort	hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/da0fbb3253a641e9a1dab25e6c597513
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A hypothalamic-thalamostriatal circuit that controls approach-avoidance conflict in rats

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