Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.

Mitochondria are involved in the regulation of cell differentiation processes, but its function changes and molecular mechanisms are not yet clear. In this study, we found that mitochondrial functions changed obviously when K562 cells were induced to megakaryocytic differentiation by phorbol 12-myri...

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Auteurs principaux: Rui Huang, Long Zhao, Hui Chen, Rong-Hua Yin, Chang-Yan Li, Yi-Qun Zhan, Jian-Hong Zhang, Chang-hui Ge, Miao Yu, Xiao-Ming Yang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/da196f3df5944096a9a79c7ad718b694
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