The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation

Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF).

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Autores principales: Erin Kate McNally, Christopher Leonard Brett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/da21f35dceab46b28e926a7fc6f011c2
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spelling oai:doaj.org-article:da21f35dceab46b28e926a7fc6f011c22021-12-02T14:39:46ZThe intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation10.1038/s41467-018-07734-52041-1723https://doaj.org/article/da21f35dceab46b28e926a7fc6f011c22018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07734-5https://doaj.org/toc/2041-1723Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF).Erin Kate McNallyChristopher Leonard BrettNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erin Kate McNally
Christopher Leonard Brett
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
description Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF).
format article
author Erin Kate McNally
Christopher Leonard Brett
author_facet Erin Kate McNally
Christopher Leonard Brett
author_sort Erin Kate McNally
title The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
title_short The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
title_full The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
title_fullStr The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
title_full_unstemmed The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
title_sort intralumenal fragment pathway mediates escrt-independent surface transporter down-regulation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/da21f35dceab46b28e926a7fc6f011c2
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