The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation
Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF).
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Nature Portfolio
2018
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oai:doaj.org-article:da21f35dceab46b28e926a7fc6f011c22021-12-02T14:39:46ZThe intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation10.1038/s41467-018-07734-52041-1723https://doaj.org/article/da21f35dceab46b28e926a7fc6f011c22018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07734-5https://doaj.org/toc/2041-1723Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF).Erin Kate McNallyChristopher Leonard BrettNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Erin Kate McNally Christopher Leonard Brett The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
description |
Cell surface receptors are thought to be internalized via the multivesicular bodies (MVBs) in an ESCRT-dependent pathway. Here, the authors report that in yeast, a hexose transporter is internalized via an ESCRT-independent pathway into intralumenal fragments (ILF). |
format |
article |
author |
Erin Kate McNally Christopher Leonard Brett |
author_facet |
Erin Kate McNally Christopher Leonard Brett |
author_sort |
Erin Kate McNally |
title |
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
title_short |
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
title_full |
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
title_fullStr |
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
title_full_unstemmed |
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation |
title_sort |
intralumenal fragment pathway mediates escrt-independent surface transporter down-regulation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/da21f35dceab46b28e926a7fc6f011c2 |
work_keys_str_mv |
AT erinkatemcnally theintralumenalfragmentpathwaymediatesescrtindependentsurfacetransporterdownregulation AT christopherleonardbrett theintralumenalfragmentpathwaymediatesescrtindependentsurfacetransporterdownregulation AT erinkatemcnally intralumenalfragmentpathwaymediatesescrtindependentsurfacetransporterdownregulation AT christopherleonardbrett intralumenalfragmentpathwaymediatesescrtindependentsurfacetransporterdownregulation |
_version_ |
1718390563466641408 |