Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism

Wenqiang Wang,1,&ast; Jia He,1,&ast; Yunhua Hu,1 Yanpeng Song,2 Xianghui Zhang,1 Heng Guo,1 Xinping Wang,1 Mulatibieke Keerman,1 Jiaolong Ma,1 Yizhong Yan,1 Jingyu Zhang,1 Rulin Ma,1 Shuxia Guo1,3 1Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang, People’...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wang W, He J, Hu Y, Song Y, Zhang X, Guo H, Wang X, Keerman M, Ma J, Yan Y, Zhang J, Ma R, Guo S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	metabolically healthy obesity cardiovascular disease rural areas epidemiology Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/da24d6e3e3b24a1b96dbaa5d062855ef
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:da24d6e3e3b24a1b96dbaa5d062855ef
record_format	dspace
spelling	oai:doaj.org-article:da24d6e3e3b24a1b96dbaa5d062855ef2021-12-02T19:16:51ZComparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism1178-7007https://doaj.org/article/da24d6e3e3b24a1b96dbaa5d062855ef2021-10-01T00:00:00Zhttps://www.dovepress.com/comparison-of-the-incidence-of-cardiovascular-diseases-in-weight-group-peer-reviewed-fulltext-article-DMSOhttps://doaj.org/toc/1178-7007Wenqiang Wang,1,&ast; Jia He,1,&ast; Yunhua Hu,1 Yanpeng Song,2 Xianghui Zhang,1 Heng Guo,1 Xinping Wang,1 Mulatibieke Keerman,1 Jiaolong Ma,1 Yizhong Yan,1 Jingyu Zhang,1 Rulin Ma,1 Shuxia Guo1,3 1Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang, People’s Republic of China; 2Department of Social Work, The First Affiliated Hospital of Shihezi University Medical College, Shihezi, Xinjiang, People’s Republic of China; 3Department of NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, The First Affiliated Hospital of Shihezi University Medical College, Shihezi, Xinjiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Shuxia GuoDepartment of Public Health, The Key Laboratory of Preventive Medicine, Building No. 1, Shihezi University School of Medicine, Suite 721, Beier Road, Shihezi, 832000, Xinjiang, People’s Republic of ChinaTel +86-1800-9932-625Fax +86-993-2057-153Email gsxshzu@sina.comRulin MaDepartment of Public Health, The Key Laboratory of Preventive Medicine, Building No. 1, Shihezi University School of Medicine, Suite 816, Beier Road, Shihezi, 832000, Xinjiang, People’s Republic of ChinaTel +86-1330-9930-561Fax +86-993-2057-153Email marulin@shzu.edu.cnBackground: We aimed to identify the relationship between metabolically healthy obesity (MHO), a special subtype of obesity, and the incidence of cardiovascular disease (CVD) in rural Xinjiang.Methods: Body mass index (BMI) and the Joint Interim Statement criteria were utilized to define obesity and metabolic status, respectively. A baseline survey was conducted between 2010 and 2012. The cohort was followed-up until 2017, including 5059 participants (2953 Uyghurs and 2106 Kazakhs) in the analysis.Results: During 6.78 years of follow-up, 471 individuals developed CVD, 10.8% (n=545) of whom were obese, and the prevalence of MHO and MHNW was 5.2% and 54.5%, respectively. Compared with metabolically healthy normal weight subjects, the subjects with MHO had an increased risk of CVD (hazard ratio [HR]=1.76, 95% confidence interval [CI]: 1.23− 2.51), while the metabolically unhealthy obesity (MUO) group had an even higher risk (HR=3.80, 95% CI: 2.87− 5.03). Additionally, there were sex differences in the relationship between BMI-metabolic status and incident CVD (Pinteraction =0.027). Compared with the subjects with MHO, those with MUO had an increased risk of CVD (HR=1.84, 95% CI: 1.26− 2.71).Conclusion: MHO was associated with a high risk of CVD among adults in rural Xinjiang. In each BMI category, metabolically unhealthy subjects had a higher risk of developing CVD than did metabolically healthy subjects.Keywords: metabolically healthy obesity, cardiovascular disease, rural areas, epidemiologyWang WHe JHu YSong YZhang XGuo HWang XKeerman MMa JYan YZhang JMa RGuo SDove Medical Pressarticlemetabolically healthy obesitycardiovascular diseaserural areasepidemiologySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 4155-4163 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	metabolically healthy obesity cardiovascular disease rural areas epidemiology Specialties of internal medicine RC581-951
spellingShingle	metabolically healthy obesity cardiovascular disease rural areas epidemiology Specialties of internal medicine RC581-951 Wang W He J Hu Y Song Y Zhang X Guo H Wang X Keerman M Ma J Yan Y Zhang J Ma R Guo S Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
description	Wenqiang Wang,1,&ast; Jia He,1,&ast; Yunhua Hu,1 Yanpeng Song,2 Xianghui Zhang,1 Heng Guo,1 Xinping Wang,1 Mulatibieke Keerman,1 Jiaolong Ma,1 Yizhong Yan,1 Jingyu Zhang,1 Rulin Ma,1 Shuxia Guo1,3 1Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang, People’s Republic of China; 2Department of Social Work, The First Affiliated Hospital of Shihezi University Medical College, Shihezi, Xinjiang, People’s Republic of China; 3Department of NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, The First Affiliated Hospital of Shihezi University Medical College, Shihezi, Xinjiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Shuxia GuoDepartment of Public Health, The Key Laboratory of Preventive Medicine, Building No. 1, Shihezi University School of Medicine, Suite 721, Beier Road, Shihezi, 832000, Xinjiang, People’s Republic of ChinaTel +86-1800-9932-625Fax +86-993-2057-153Email gsxshzu@sina.comRulin MaDepartment of Public Health, The Key Laboratory of Preventive Medicine, Building No. 1, Shihezi University School of Medicine, Suite 816, Beier Road, Shihezi, 832000, Xinjiang, People’s Republic of ChinaTel +86-1330-9930-561Fax +86-993-2057-153Email marulin@shzu.edu.cnBackground: We aimed to identify the relationship between metabolically healthy obesity (MHO), a special subtype of obesity, and the incidence of cardiovascular disease (CVD) in rural Xinjiang.Methods: Body mass index (BMI) and the Joint Interim Statement criteria were utilized to define obesity and metabolic status, respectively. A baseline survey was conducted between 2010 and 2012. The cohort was followed-up until 2017, including 5059 participants (2953 Uyghurs and 2106 Kazakhs) in the analysis.Results: During 6.78 years of follow-up, 471 individuals developed CVD, 10.8% (n=545) of whom were obese, and the prevalence of MHO and MHNW was 5.2% and 54.5%, respectively. Compared with metabolically healthy normal weight subjects, the subjects with MHO had an increased risk of CVD (hazard ratio [HR]=1.76, 95% confidence interval [CI]: 1.23− 2.51), while the metabolically unhealthy obesity (MUO) group had an even higher risk (HR=3.80, 95% CI: 2.87− 5.03). Additionally, there were sex differences in the relationship between BMI-metabolic status and incident CVD (Pinteraction =0.027). Compared with the subjects with MHO, those with MUO had an increased risk of CVD (HR=1.84, 95% CI: 1.26− 2.71).Conclusion: MHO was associated with a high risk of CVD among adults in rural Xinjiang. In each BMI category, metabolically unhealthy subjects had a higher risk of developing CVD than did metabolically healthy subjects.Keywords: metabolically healthy obesity, cardiovascular disease, rural areas, epidemiology
format	article
author	Wang W He J Hu Y Song Y Zhang X Guo H Wang X Keerman M Ma J Yan Y Zhang J Ma R Guo S
author_facet	Wang W He J Hu Y Song Y Zhang X Guo H Wang X Keerman M Ma J Yan Y Zhang J Ma R Guo S
author_sort	Wang W
title	Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
title_short	Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
title_full	Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
title_fullStr	Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
title_full_unstemmed	Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism
title_sort	comparison of the incidence of cardiovascular diseases in weight groups with healthy and unhealthy metabolism
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/da24d6e3e3b24a1b96dbaa5d062855ef
work_keys_str_mv	AT wangw comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT hej comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT huy comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT songy comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT zhangx comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT guoh comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT wangx comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT keermanm comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT maj comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT yany comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT zhangj comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT mar comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism AT guos comparisonoftheincidenceofcardiovasculardiseasesinweightgroupswithhealthyandunhealthymetabolism
_version_	1718376942383661056

Comparison of the Incidence of Cardiovascular Diseases in Weight Groups with Healthy and Unhealthy Metabolism

Ejemplares similares