Modern possibilities and prospects of early diagnosis of stomach cancer

The review includes 70 articles, most of which have been published for the last 5 years.The aim of the review: explore the modern possibilities and prospects of early diagnosis of stomach cancer. In 2018 in Russia, the mortality rate within one year after the diagnosis was 47.4%. Leading experts in...

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Autores principales:	A. A. Arkhipova, V. V. Anischenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2021
Materias:	biomarkers stomach ulcer cancer risk factors diagnostics microrna Science Q
Acceso en línea:	https://doaj.org/article/da2a40afa65a45f0891bb2df573865e1
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id	oai:doaj.org-article:da2a40afa65a45f0891bb2df573865e1
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spelling	oai:doaj.org-article:da2a40afa65a45f0891bb2df573865e12021-11-23T06:14:46ZModern possibilities and prospects of early diagnosis of stomach cancer2541-94202587-959610.29413/ABS.2021-6.3.12https://doaj.org/article/da2a40afa65a45f0891bb2df573865e12021-08-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2854https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The review includes 70 articles, most of which have been published for the last 5 years.The aim of the review: explore the modern possibilities and prospects of early diagnosis of stomach cancer. In 2018 in Russia, the mortality rate within one year after the diagnosis was 47.4%. Leading experts in luminal endoscopy from Japan, where more than 60% cases of stomach cancer are detected at an early stage, recommend using advanced endoscopic equipment for routine diagnostics, which allows enlarging the image, examining the capillaries of the mucosa and taking series of pictures. Artificial intelligence improves accuracy. Gastroscopic study with artificial intelligence compensates errors and limited capabilities of people, and provides greater accuracy. However, this technology is expensive, and esophagogastroduodenoscopy itself is an invasive method and can be used only in a clinical setting. In patients with a detectable lesion, a biopsy should be performed. It is important to obtain a sufficient amount of tissue when collecting material, however, many patients take anticoagulants, and thus sampling of numerous fragments can lead to bleeding. Given the limitations of esophagogastroduodenoscopy with biopsy and the fact that only 12.4% cases of stomach cancer in 2018 in Russia identified on the stage I, the searching of effective diagnostic tools is still relevant. MicroRNAs have been in the «cancer research arena» for over 10 years and are considered biomarkers that can help to differentiate between the patients with normal range, dysplasia and those with cancer. MicroRNA regulates all vital processes of a cell, moreover, they are stable and easily extracted from various biological materials, including tissues, blood, feces, saliva, ascitic fluid and even paraffin blocks. And although microRNAs are only entering clinical practice, the results obtained are encouraging.A. A. ArkhipovaV. V. AnischenkoScientific Сentre for Family Health and Human Reproduction Problemsarticlebiomarkersstomach ulcercancerrisk factorsdiagnosticsmicrornaScienceQRUActa Biomedica Scientifica, Vol 6, Iss 3, Pp 113-125 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	biomarkers stomach ulcer cancer risk factors diagnostics microrna Science Q
spellingShingle	biomarkers stomach ulcer cancer risk factors diagnostics microrna Science Q A. A. Arkhipova V. V. Anischenko Modern possibilities and prospects of early diagnosis of stomach cancer
description	The review includes 70 articles, most of which have been published for the last 5 years.The aim of the review: explore the modern possibilities and prospects of early diagnosis of stomach cancer. In 2018 in Russia, the mortality rate within one year after the diagnosis was 47.4%. Leading experts in luminal endoscopy from Japan, where more than 60% cases of stomach cancer are detected at an early stage, recommend using advanced endoscopic equipment for routine diagnostics, which allows enlarging the image, examining the capillaries of the mucosa and taking series of pictures. Artificial intelligence improves accuracy. Gastroscopic study with artificial intelligence compensates errors and limited capabilities of people, and provides greater accuracy. However, this technology is expensive, and esophagogastroduodenoscopy itself is an invasive method and can be used only in a clinical setting. In patients with a detectable lesion, a biopsy should be performed. It is important to obtain a sufficient amount of tissue when collecting material, however, many patients take anticoagulants, and thus sampling of numerous fragments can lead to bleeding. Given the limitations of esophagogastroduodenoscopy with biopsy and the fact that only 12.4% cases of stomach cancer in 2018 in Russia identified on the stage I, the searching of effective diagnostic tools is still relevant. MicroRNAs have been in the «cancer research arena» for over 10 years and are considered biomarkers that can help to differentiate between the patients with normal range, dysplasia and those with cancer. MicroRNA regulates all vital processes of a cell, moreover, they are stable and easily extracted from various biological materials, including tissues, blood, feces, saliva, ascitic fluid and even paraffin blocks. And although microRNAs are only entering clinical practice, the results obtained are encouraging.
format	article
author	A. A. Arkhipova V. V. Anischenko
author_facet	A. A. Arkhipova V. V. Anischenko
author_sort	A. A. Arkhipova
title	Modern possibilities and prospects of early diagnosis of stomach cancer
title_short	Modern possibilities and prospects of early diagnosis of stomach cancer
title_full	Modern possibilities and prospects of early diagnosis of stomach cancer
title_fullStr	Modern possibilities and prospects of early diagnosis of stomach cancer
title_full_unstemmed	Modern possibilities and prospects of early diagnosis of stomach cancer
title_sort	modern possibilities and prospects of early diagnosis of stomach cancer
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2021
url	https://doaj.org/article/da2a40afa65a45f0891bb2df573865e1
work_keys_str_mv	AT aaarkhipova modernpossibilitiesandprospectsofearlydiagnosisofstomachcancer AT vvanischenko modernpossibilitiesandprospectsofearlydiagnosisofstomachcancer
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Modern possibilities and prospects of early diagnosis of stomach cancer

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