<named-content content-type="genus-species">Plasmodium falciparum</named-content> Apicomplexan-Specific Glucosamine-6-Phosphate <italic toggle="yes">N</italic>-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development

<named-content content-type="genus-species">Plasmodium falciparum</named-content> Apicomplexan-Specific Glucosamine-6-Phosphate <italic toggle="yes">N</italic>-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development

ABSTRACT UDP-N-acetylglucosamine (UDP-GlcNAc), the main product of the hexosamine biosynthetic pathway, is an important metabolite in protozoan parasites since its sugar moiety is incorporated into glycosylphosphatidylinositol (GPI) glycolipids and N- and O-linked glycans. Apicomplexan parasites hav...

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Bibliographic Details
Main Authors: Jordi Chi, Marta Cova, Matilde de las Rivas, Ana Medina, Rafael Junqueira Borges, Pablo Leivar, Antoni Planas, Isabel Usón, Ramón Hurtado-Guerrero, Luis Izquierdo
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
malaria
metabolism
Plasmodium falciparum
UDP-N-acetylglucosamine
aminosugar pathway
apicomplexan parasites
Microbiology
QR1-502
Online Access:https://doaj.org/article/da2c32c5b5074e7db65d426fcd77c42a
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