Alteration of serum amino acid profiles by dietary adenine supplementation inhibits fatty liver development in rats
Abstract Studies on animal models have demonstrated that feeding a low-arginine diet inhibits triacylglycerol (TAG) secretion from the liver, resulting in marked fatty liver development in rats. Here, we first showed that culturing hepatocytes in the medium mimicking the serum amino acid profile of...
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Main Authors: | Hiroki Nishi, Daisuke Yamanaka, Masato Masuda, Yuki Goda, Koichi Ito, Fumihiko Hakuno, Shin-Ichiro Takahashi |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/da3c335dee9348e3be7270e3b497e1fa |
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