Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones

Managing bone tissue regeneration is a key problem in traumatology and orthopedics. The researches proved that thyroid hormones affect hemostasis and reparative regeneration of bone tissue favorably and promote osteogenesis and bone consolidation. The aim of this research is to study the influence o...

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Autores principales:	Q. .. Guangda, S. A. Lepekhova, L. V. Zaritskaya, L. V. Rodionova, N. V. Tishkov, I. S. Kurganskiy, O. A. Goldberg, Y. I. Pivovarov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	bone regeneration neoarthrosis thyroid hormones Science Q
Acceso en línea:	https://doaj.org/article/da4a744798e94b11a876280c66d6753d
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spelling	oai:doaj.org-article:da4a744798e94b11a876280c66d6753d2021-11-23T06:14:35ZInfluence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones2541-94202587-959610.12737/22981https://doaj.org/article/da4a744798e94b11a876280c66d6753d2016-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/252https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Managing bone tissue regeneration is a key problem in traumatology and orthopedics. The researches proved that thyroid hormones affect hemostasis and reparative regeneration of bone tissue favorably and promote osteogenesis and bone consolidation. The aim of this research is to study the influence of disturbed reparative regeneration on the concentration of thyroid hormones in blood in the dynamics. Experimental research on rabbits (n = 12) with modelling of disturbed reparative regeneration revealed disorder in thyroid hormones synthesis and different directions of T3 and unbound T3 production on the 35th day when the maximum decrease of T3 (2 times) and unbound T3 (1.5 times) compared to normal values was registered. The analysis of production of T4 and unbound T4 revealed suppression of the values from the 1st to 50th day and gradual increase in unbound T4 from the 50th day. The most significant manifestation of thyroid gland reaction on the disturbed reparative regeneration of shin bones was the decrease in T3 and peripheral conversion of thyroid hormones up to 50th day with formation of false joint in these terms.Q. .. GuangdaS. A. LepekhovaL. V. ZaritskayaL. V. RodionovaN. V. TishkovI. S. KurganskiyO. A. GoldbergY. I. PivovarovScientific Сentre for Family Health and Human Reproduction Problemsarticlebone regenerationneoarthrosisthyroid hormonesScienceQRUActa Biomedica Scientifica, Vol 1, Iss 4, Pp 109-114 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	bone regeneration neoarthrosis thyroid hormones Science Q
spellingShingle	bone regeneration neoarthrosis thyroid hormones Science Q Q. .. Guangda S. A. Lepekhova L. V. Zaritskaya L. V. Rodionova N. V. Tishkov I. S. Kurganskiy O. A. Goldberg Y. I. Pivovarov Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
description	Managing bone tissue regeneration is a key problem in traumatology and orthopedics. The researches proved that thyroid hormones affect hemostasis and reparative regeneration of bone tissue favorably and promote osteogenesis and bone consolidation. The aim of this research is to study the influence of disturbed reparative regeneration on the concentration of thyroid hormones in blood in the dynamics. Experimental research on rabbits (n = 12) with modelling of disturbed reparative regeneration revealed disorder in thyroid hormones synthesis and different directions of T3 and unbound T3 production on the 35th day when the maximum decrease of T3 (2 times) and unbound T3 (1.5 times) compared to normal values was registered. The analysis of production of T4 and unbound T4 revealed suppression of the values from the 1st to 50th day and gradual increase in unbound T4 from the 50th day. The most significant manifestation of thyroid gland reaction on the disturbed reparative regeneration of shin bones was the decrease in T3 and peripheral conversion of thyroid hormones up to 50th day with formation of false joint in these terms.
format	article
author	Q. .. Guangda S. A. Lepekhova L. V. Zaritskaya L. V. Rodionova N. V. Tishkov I. S. Kurganskiy O. A. Goldberg Y. I. Pivovarov
author_facet	Q. .. Guangda S. A. Lepekhova L. V. Zaritskaya L. V. Rodionova N. V. Tishkov I. S. Kurganskiy O. A. Goldberg Y. I. Pivovarov
author_sort	Q. .. Guangda
title	Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
title_short	Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
title_full	Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
title_fullStr	Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
title_full_unstemmed	Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
title_sort	influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/da4a744798e94b11a876280c66d6753d
work_keys_str_mv	AT qguangda influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT salepekhova influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT lvzaritskaya influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT lvrodionova influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT nvtishkov influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT iskurganskiy influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT oagoldberg influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones AT yipivovarov influenceofdisturbedconditionsofreparativeregenerationofbonetissueonthedynamicsofthyroidhormones
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Influence of disturbed conditions of reparative regeneration of bone tissue on the dynamics of thyroid hormones

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