High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.

<h4>Purpose</h4>High resolution flat-panel computed tomography arthrography (FPCT-A) and magnetic resonance arthrography (MR-A) are well suited to evaluate osteochondral lesions. The current study compares the performance of FPCT-A versus MR-A in an experimental setting.<h4>Methods...

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Autores principales:	Gesa H Pöhler, Lena Sonnow, Sarah Ettinger, Alexandra Rahn, Filip Klimes, Christoph Becher, Christian von Falck, Frank K Wacker, Christian Plaass
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/da534cf21e304c268538d1969431fb39
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spelling	oai:doaj.org-article:da534cf21e304c268538d1969431fb392021-12-02T20:18:28ZHigh resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.1932-620310.1371/journal.pone.0255616https://doaj.org/article/da534cf21e304c268538d1969431fb392021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255616https://doaj.org/toc/1932-6203<h4>Purpose</h4>High resolution flat-panel computed tomography arthrography (FPCT-A) and magnetic resonance arthrography (MR-A) are well suited to evaluate osteochondral lesions. The current study compares the performance of FPCT-A versus MR-A in an experimental setting.<h4>Methods</h4>Fourteen cadaveric ankles were prepared with artificial osteochondral defects of various sizes in four separate talar locations. After intra-articular contrast injection, FPCT-A and 3-T MR-A were acquired. Each defect was then filled with synthetic pallets. The resulting cast was used as reference. Two independent radiologists measured the dimensions of all defects with FPCT-A and MR-A. Intra-class correlation coefficients (ICC) were calculated. Data were compared using t-tests and Bland-Altman plots.<h4>Results</h4>The correlation for FPCT-A and cast was higher compared to MR-A and cast (ICC 0.876 vs. 0.799 for surface [length x width]; ICC 0.887 vs. 0.866 for depth, p<0.001). Mean differences between FPCT-A and cast measurements were -1.1 mm for length (p<0.001), -0.7 mm for width (p<0.001) and -0.4 mm for depth (p = 0.023). By MR-A, there were no significant differences for length and width compared to cast (p>0.05). Depth measurements were significantly smaller by MR-A (mean difference -1.1 mm, p<0.001). There was no bias between the different modalities.<h4>Conclusions</h4>Ex vivo FPCT-A and MR-A both deliver high diagnostic accuracy for the evaluation of osteochondral defects. FPCT-A was slightly more accurate than MR-A, which was most significant when measuring lesion depth.Gesa H PöhlerLena SonnowSarah EttingerAlexandra RahnFilip KlimesChristoph BecherChristian von FalckFrank K WackerChristian PlaassPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255616 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Gesa H Pöhler Lena Sonnow Sarah Ettinger Alexandra Rahn Filip Klimes Christoph Becher Christian von Falck Frank K Wacker Christian Plaass High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
description	<h4>Purpose</h4>High resolution flat-panel computed tomography arthrography (FPCT-A) and magnetic resonance arthrography (MR-A) are well suited to evaluate osteochondral lesions. The current study compares the performance of FPCT-A versus MR-A in an experimental setting.<h4>Methods</h4>Fourteen cadaveric ankles were prepared with artificial osteochondral defects of various sizes in four separate talar locations. After intra-articular contrast injection, FPCT-A and 3-T MR-A were acquired. Each defect was then filled with synthetic pallets. The resulting cast was used as reference. Two independent radiologists measured the dimensions of all defects with FPCT-A and MR-A. Intra-class correlation coefficients (ICC) were calculated. Data were compared using t-tests and Bland-Altman plots.<h4>Results</h4>The correlation for FPCT-A and cast was higher compared to MR-A and cast (ICC 0.876 vs. 0.799 for surface [length x width]; ICC 0.887 vs. 0.866 for depth, p<0.001). Mean differences between FPCT-A and cast measurements were -1.1 mm for length (p<0.001), -0.7 mm for width (p<0.001) and -0.4 mm for depth (p = 0.023). By MR-A, there were no significant differences for length and width compared to cast (p>0.05). Depth measurements were significantly smaller by MR-A (mean difference -1.1 mm, p<0.001). There was no bias between the different modalities.<h4>Conclusions</h4>Ex vivo FPCT-A and MR-A both deliver high diagnostic accuracy for the evaluation of osteochondral defects. FPCT-A was slightly more accurate than MR-A, which was most significant when measuring lesion depth.
format	article
author	Gesa H Pöhler Lena Sonnow Sarah Ettinger Alexandra Rahn Filip Klimes Christoph Becher Christian von Falck Frank K Wacker Christian Plaass
author_facet	Gesa H Pöhler Lena Sonnow Sarah Ettinger Alexandra Rahn Filip Klimes Christoph Becher Christian von Falck Frank K Wacker Christian Plaass
author_sort	Gesa H Pöhler
title	High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
title_short	High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
title_full	High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
title_fullStr	High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
title_full_unstemmed	High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
title_sort	high resolution flat-panel ct arthrography vs. mr arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/da534cf21e304c268538d1969431fb39
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High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.

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