Multiple states in ongoing neural activity in the rat visual cortex.

The brain continuously produces internal activity in the absence of afferently salient sensory input. Spontaneous neural activity is intrinsically defined by circuit structures and associated with the mode of information processing and behavioral responses. However, the spatiotemporal dynamics of sp...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Daichi Konno, Shinji Nishimoto, Takafumi Suzuki, Yuji Ikegaya, Nobuyoshi Matsumoto
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/da5ecdeab20646c68191426a25bff23d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:da5ecdeab20646c68191426a25bff23d
record_format	dspace
spelling	oai:doaj.org-article:da5ecdeab20646c68191426a25bff23d2021-12-02T20:19:28ZMultiple states in ongoing neural activity in the rat visual cortex.1932-620310.1371/journal.pone.0256791https://doaj.org/article/da5ecdeab20646c68191426a25bff23d2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256791https://doaj.org/toc/1932-6203The brain continuously produces internal activity in the absence of afferently salient sensory input. Spontaneous neural activity is intrinsically defined by circuit structures and associated with the mode of information processing and behavioral responses. However, the spatiotemporal dynamics of spontaneous activity in the visual cortices of behaving animals remain almost elusive. Using a custom-made electrode array, we recorded 32-site electrocorticograms in the primary and secondary visual cortex of freely behaving rats and determined the propagation patterns of spontaneous neural activity. Nonlinear dimensionality reduction and unsupervised clustering revealed multiple discrete states of the activity patterns. The activity remained stable in one state and suddenly jumped to another state. The diversity and dynamics of the internally switching cortical states would imply flexibility of neural responses to various external inputs.Daichi KonnoShinji NishimotoTakafumi SuzukiYuji IkegayaNobuyoshi MatsumotoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0256791 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Daichi Konno Shinji Nishimoto Takafumi Suzuki Yuji Ikegaya Nobuyoshi Matsumoto Multiple states in ongoing neural activity in the rat visual cortex.
description	The brain continuously produces internal activity in the absence of afferently salient sensory input. Spontaneous neural activity is intrinsically defined by circuit structures and associated with the mode of information processing and behavioral responses. However, the spatiotemporal dynamics of spontaneous activity in the visual cortices of behaving animals remain almost elusive. Using a custom-made electrode array, we recorded 32-site electrocorticograms in the primary and secondary visual cortex of freely behaving rats and determined the propagation patterns of spontaneous neural activity. Nonlinear dimensionality reduction and unsupervised clustering revealed multiple discrete states of the activity patterns. The activity remained stable in one state and suddenly jumped to another state. The diversity and dynamics of the internally switching cortical states would imply flexibility of neural responses to various external inputs.
format	article
author	Daichi Konno Shinji Nishimoto Takafumi Suzuki Yuji Ikegaya Nobuyoshi Matsumoto
author_facet	Daichi Konno Shinji Nishimoto Takafumi Suzuki Yuji Ikegaya Nobuyoshi Matsumoto
author_sort	Daichi Konno
title	Multiple states in ongoing neural activity in the rat visual cortex.
title_short	Multiple states in ongoing neural activity in the rat visual cortex.
title_full	Multiple states in ongoing neural activity in the rat visual cortex.
title_fullStr	Multiple states in ongoing neural activity in the rat visual cortex.
title_full_unstemmed	Multiple states in ongoing neural activity in the rat visual cortex.
title_sort	multiple states in ongoing neural activity in the rat visual cortex.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/da5ecdeab20646c68191426a25bff23d
work_keys_str_mv	AT daichikonno multiplestatesinongoingneuralactivityintheratvisualcortex AT shinjinishimoto multiplestatesinongoingneuralactivityintheratvisualcortex AT takafumisuzuki multiplestatesinongoingneuralactivityintheratvisualcortex AT yujiikegaya multiplestatesinongoingneuralactivityintheratvisualcortex AT nobuyoshimatsumoto multiplestatesinongoingneuralactivityintheratvisualcortex
_version_	1718374196151582720

Multiple states in ongoing neural activity in the rat visual cortex.

Ejemplares similares