Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology

Existing fluorescent protein-based sensor measurements are limited to 4 or fewer simultaneously recorded modalities due to spectral overlap. Here the authors introduce Multiplexed Optical Sensors in Arrayed Islands of Cells (MOSAIC), which enables parallel recording of tens of physiological paramete...

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Autores principales:	Christopher A. Werley, Stefano Boccardo, Alessandra Rigamonti, Emil M. Hansson, Adam E. Cohen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/da5fa069ae7f4bf7a1f2a81128754790
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spelling	oai:doaj.org-article:da5fa069ae7f4bf7a1f2a811287547902021-12-02T14:53:44ZMultiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology10.1038/s41467-020-17607-52041-1723https://doaj.org/article/da5fa069ae7f4bf7a1f2a811287547902020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17607-5https://doaj.org/toc/2041-1723Existing fluorescent protein-based sensor measurements are limited to 4 or fewer simultaneously recorded modalities due to spectral overlap. Here the authors introduce Multiplexed Optical Sensors in Arrayed Islands of Cells (MOSAIC), which enables parallel recording of tens of physiological parameters using dense arrays of cell islands, each expressing a different fluorescent sensor.Christopher A. WerleyStefano BoccardoAlessandra RigamontiEmil M. HanssonAdam E. CohenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher A. Werley Stefano Boccardo Alessandra Rigamonti Emil M. Hansson Adam E. Cohen Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
description	Existing fluorescent protein-based sensor measurements are limited to 4 or fewer simultaneously recorded modalities due to spectral overlap. Here the authors introduce Multiplexed Optical Sensors in Arrayed Islands of Cells (MOSAIC), which enables parallel recording of tens of physiological parameters using dense arrays of cell islands, each expressing a different fluorescent sensor.
format	article
author	Christopher A. Werley Stefano Boccardo Alessandra Rigamonti Emil M. Hansson Adam E. Cohen
author_facet	Christopher A. Werley Stefano Boccardo Alessandra Rigamonti Emil M. Hansson Adam E. Cohen
author_sort	Christopher A. Werley
title	Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
title_short	Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
title_full	Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
title_fullStr	Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
title_full_unstemmed	Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
title_sort	multiplexed optical sensors in arrayed islands of cells for multimodal recordings of cellular physiology
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/da5fa069ae7f4bf7a1f2a81128754790
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Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology

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