Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting

Curvature-mediating proteins are known to induce specific membrane shapes, but whether motorprotein-lipid interactions remodel membranes too remains unclear. Here authors show that curvature-dependent lipid interactions of myosin-VI remodel the membrane geometry into dynamic spatial patterns.

Guardado en:

Detalles Bibliográficos
Autores principales:	Benoit Rogez, Laeschkir Würthner, Anastasiia B. Petrova, Felix B. Zierhut, Dario Saczko-Brack, Maria-Ana Huergo, Christopher Batters, Erwin Frey, Claudia Veigel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/da69c820db8b4ae1b1ef6a2cc0804e10
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:da69c820db8b4ae1b1ef6a2cc0804e10
record_format	dspace
spelling	oai:doaj.org-article:da69c820db8b4ae1b1ef6a2cc0804e102021-12-02T16:57:52ZReconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting10.1038/s41467-019-11268-92041-1723https://doaj.org/article/da69c820db8b4ae1b1ef6a2cc0804e102019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11268-9https://doaj.org/toc/2041-1723Curvature-mediating proteins are known to induce specific membrane shapes, but whether motorprotein-lipid interactions remodel membranes too remains unclear. Here authors show that curvature-dependent lipid interactions of myosin-VI remodel the membrane geometry into dynamic spatial patterns.Benoit RogezLaeschkir WürthnerAnastasiia B. PetrovaFelix B. ZierhutDario Saczko-BrackMaria-Ana HuergoChristopher BattersErwin FreyClaudia VeigelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benoit Rogez Laeschkir Würthner Anastasiia B. Petrova Felix B. Zierhut Dario Saczko-Brack Maria-Ana Huergo Christopher Batters Erwin Frey Claudia Veigel Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
description	Curvature-mediating proteins are known to induce specific membrane shapes, but whether motorprotein-lipid interactions remodel membranes too remains unclear. Here authors show that curvature-dependent lipid interactions of myosin-VI remodel the membrane geometry into dynamic spatial patterns.
format	article
author	Benoit Rogez Laeschkir Würthner Anastasiia B. Petrova Felix B. Zierhut Dario Saczko-Brack Maria-Ana Huergo Christopher Batters Erwin Frey Claudia Veigel
author_facet	Benoit Rogez Laeschkir Würthner Anastasiia B. Petrova Felix B. Zierhut Dario Saczko-Brack Maria-Ana Huergo Christopher Batters Erwin Frey Claudia Veigel
author_sort	Benoit Rogez
title	Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
title_short	Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
title_full	Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
title_fullStr	Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
title_full_unstemmed	Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting
title_sort	reconstitution reveals how myosin-vi self-organises to generate a dynamic mechanism of membrane sculpting
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/da69c820db8b4ae1b1ef6a2cc0804e10
work_keys_str_mv	AT benoitrogez reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT laeschkirwurthner reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT anastasiiabpetrova reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT felixbzierhut reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT dariosaczkobrack reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT mariaanahuergo reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT christopherbatters reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT erwinfrey reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting AT claudiaveigel reconstitutionrevealshowmyosinviselforganisestogenerateadynamicmechanismofmembranesculpting
_version_	1718382476006522880

Reconstitution reveals how myosin-VI self-organises to generate a dynamic mechanism of membrane sculpting

Ejemplares similares