Composition of receptor tyrosine kinase-mediated lipid micro-domains controlled by adaptor protein interaction

Abstract Receptor tyrosine kinases (RTKs) are highly regulated, single pass transmembrane proteins, fundamental to cellular function and survival. Aberrancies in regulation lead to corruption of signal transduction and a range of pathological outcomes. Although control mechanisms associated with the...

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Autores principales: Arndt Rohwedder, Sabine Knipp, Lee D. Roberts, John E. Ladbury
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/da6ab08961324858bf419780f90c8fa2
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