Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

Here, the authors identify interleukin-3 as a predictive marker for severity and outcome of SARS-CoV-2 infection in a multi-center, prospective study and find that patients with severe COVID-19 have reduced circulating plasmacytoid dendritic cell levels compared to non-severe COVID-19 patients.

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Autores principales: Alan Bénard, Anne Jacobsen, Maximilian Brunner, Christian Krautz, Bettina Klösch, Izabela Swierzy, Elisabeth Naschberger, Malgorzata J. Podolska, Dina Kouhestani, Paul David, Torsten Birkholz, Ixchel Castellanos, Denis Trufa, Horia Sirbu, Marcel Vetter, Andreas E. Kremer, Kai Hildner, Andreas Hecker, Fabian Edinger, Matthias Tenbusch, Petra Mühl-Zürbes, Alexander Steinkasserer, Enrico Richter, Hendrik Streeck, Marc M. Berger, Thorsten Brenner, Markus A. Weigand, Filip K. Swirski, Georg Schett, Robert Grützmann, Georg F. Weber
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/da75b62b7c584d48a9ba0f701d8cd0cf
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spelling oai:doaj.org-article:da75b62b7c584d48a9ba0f701d8cd0cf2021-12-02T14:03:49ZInterleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections10.1038/s41467-021-21310-42041-1723https://doaj.org/article/da75b62b7c584d48a9ba0f701d8cd0cf2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21310-4https://doaj.org/toc/2041-1723Here, the authors identify interleukin-3 as a predictive marker for severity and outcome of SARS-CoV-2 infection in a multi-center, prospective study and find that patients with severe COVID-19 have reduced circulating plasmacytoid dendritic cell levels compared to non-severe COVID-19 patients.Alan BénardAnne JacobsenMaximilian BrunnerChristian KrautzBettina KlöschIzabela SwierzyElisabeth NaschbergerMalgorzata J. PodolskaDina KouhestaniPaul DavidTorsten BirkholzIxchel CastellanosDenis TrufaHoria SirbuMarcel VetterAndreas E. KremerKai HildnerAndreas HeckerFabian EdingerMatthias TenbuschPetra Mühl-ZürbesAlexander SteinkassererEnrico RichterHendrik StreeckMarc M. BergerThorsten BrennerMarkus A. WeigandFilip K. SwirskiGeorg SchettRobert GrützmannGeorg F. WeberNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alan Bénard
Anne Jacobsen
Maximilian Brunner
Christian Krautz
Bettina Klösch
Izabela Swierzy
Elisabeth Naschberger
Malgorzata J. Podolska
Dina Kouhestani
Paul David
Torsten Birkholz
Ixchel Castellanos
Denis Trufa
Horia Sirbu
Marcel Vetter
Andreas E. Kremer
Kai Hildner
Andreas Hecker
Fabian Edinger
Matthias Tenbusch
Petra Mühl-Zürbes
Alexander Steinkasserer
Enrico Richter
Hendrik Streeck
Marc M. Berger
Thorsten Brenner
Markus A. Weigand
Filip K. Swirski
Georg Schett
Robert Grützmann
Georg F. Weber
Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
description Here, the authors identify interleukin-3 as a predictive marker for severity and outcome of SARS-CoV-2 infection in a multi-center, prospective study and find that patients with severe COVID-19 have reduced circulating plasmacytoid dendritic cell levels compared to non-severe COVID-19 patients.
format article
author Alan Bénard
Anne Jacobsen
Maximilian Brunner
Christian Krautz
Bettina Klösch
Izabela Swierzy
Elisabeth Naschberger
Malgorzata J. Podolska
Dina Kouhestani
Paul David
Torsten Birkholz
Ixchel Castellanos
Denis Trufa
Horia Sirbu
Marcel Vetter
Andreas E. Kremer
Kai Hildner
Andreas Hecker
Fabian Edinger
Matthias Tenbusch
Petra Mühl-Zürbes
Alexander Steinkasserer
Enrico Richter
Hendrik Streeck
Marc M. Berger
Thorsten Brenner
Markus A. Weigand
Filip K. Swirski
Georg Schett
Robert Grützmann
Georg F. Weber
author_facet Alan Bénard
Anne Jacobsen
Maximilian Brunner
Christian Krautz
Bettina Klösch
Izabela Swierzy
Elisabeth Naschberger
Malgorzata J. Podolska
Dina Kouhestani
Paul David
Torsten Birkholz
Ixchel Castellanos
Denis Trufa
Horia Sirbu
Marcel Vetter
Andreas E. Kremer
Kai Hildner
Andreas Hecker
Fabian Edinger
Matthias Tenbusch
Petra Mühl-Zürbes
Alexander Steinkasserer
Enrico Richter
Hendrik Streeck
Marc M. Berger
Thorsten Brenner
Markus A. Weigand
Filip K. Swirski
Georg Schett
Robert Grützmann
Georg F. Weber
author_sort Alan Bénard
title Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
title_short Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
title_full Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
title_fullStr Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
title_full_unstemmed Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
title_sort interleukin-3 is a predictive marker for severity and outcome during sars-cov-2 infections
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/da75b62b7c584d48a9ba0f701d8cd0cf
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