Dilated cardiomyopathy associated with celiac disease: A case report

Abstract Background: Celiac disease, an immune‐mediated inflammation of the small intestine, occurs in genetically predisposed individuals, and is caused by sensitivity to dietary gluten and related proteins. The global prevalence is approximately 1%. Celiac disease is frequently associated with ext...

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Bibliographic Details
Main Authors: Salma Elnour, Maram Hashim, Halah Ibrahim
Format: article
Language:EN
Published: Wiley 2021
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R
Online Access:https://doaj.org/article/da78a0fda1574e199e11dbcaba111c13
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Summary:Abstract Background: Celiac disease, an immune‐mediated inflammation of the small intestine, occurs in genetically predisposed individuals, and is caused by sensitivity to dietary gluten and related proteins. The global prevalence is approximately 1%. Celiac disease is frequently associated with extra‐intestinal manifestations, including iron deficiency anemia, dermatologic eruptions, type 1 diabetes mellitus, thyroid disease, and connective tissue disorders, but is rarely associated with cardiomyopathy.Case presentation: Our case describes a 33‐year‐old woman, who presented with exertional dyspnea and fatigue, and was diagnosed with severe iron deficiency anemia and dilated cardiomyopathy, secondary to celiac disease. Conclusion: High clinical suspicion is needed to identify celiac disease in patients diagnosed with dilated cardiomyopathy, as an improvement in cardiac function has been reported with strict adherence to a gluten‐free diet.