Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional Substitutes
Abstract Angelica sinensis (AS), one of the most versatile herbal medicines remains widely used due to its multi-faceted pharmacologic activities. Besides its traditional use as the blood-nourishing tonic, its anti-hypertensive, anti-cardiovascular, neuroprotective and anti-cancer effects have been...
Guardado en:
Autores principales: | Wei-Ren Chen, Youqing Yu, Muhammad Zulfajri, Ping-Cheng Lin, Chia C. Wang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/da7c7d48d2a2420e94f3d325c228d57a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer
por: Meng-Chuan Chen, et al.
Publicado: (2017) -
Hemoglobin affinity in Andean rodents
por: OSTOJIC,HRVOJ, et al.
Publicado: (2002) -
Hemoglobin affinity for oxygen in three subspecies of toads (Bufo sp.) living at different altitudes
por: OSTOJIC,HRVOJ, et al.
Publicado: (2000) -
Acclimation to prolonged hypoxia alters hemoglobin isoform expression and increases hemoglobin oxygen affinity and aerobic performance in a marine fish
por: Yihang K. Pan, et al.
Publicado: (2017) -
Full-length transcriptome analysis provides new insights into the early bolting occurrence in medicinal Angelica sinensis
por: Xue Gao, et al.
Publicado: (2021)