Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor

BACKGROUND AND OBJECTIVE: Corticosteroids have been used for pregnant women for fetal lung maturation but there are many controversies about their effects and side-effects, the aim of this study was to determine the effects of betamethasone on the hemodynamic changes (heart rate and blood pressure)...

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Autores principales:	M Javadian Kutenaie, Z Bouzari, A Rouhipour
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2009
Materias:	betamethasone preterm labor hemodynamic changes heart rate blood pressure Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/daa31bd5c4ca4d979f5edf4b93ba06db
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spelling	oai:doaj.org-article:daa31bd5c4ca4d979f5edf4b93ba06db2021-11-10T09:03:00ZEffect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor1561-41072251-7170https://doaj.org/article/daa31bd5c4ca4d979f5edf4b93ba06db2009-10-01T00:00:00Zhttp://jbums.org/article-1-3255-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Corticosteroids have been used for pregnant women for fetal lung maturation but there are many controversies about their effects and side-effects, the aim of this study was to determine the effects of betamethasone on the hemodynamic changes (heart rate and blood pressure) in pregnant women.METHODS: This clinical trial study performed on 100 pregnant women at risk of preterm delivery between 24-34 weeks of gestation in Yahyanejad hospital in Babol (2006). Betamethasone was injected 12 mg (2 doses with 12 hours interval, IM) and systolic blood pressure, diastolic blood pressure and heart rate were measured before injection (2 times with 5 minute interval) and after first and second dose injection (after each dose 2 times with 2 hours interval). The data were analyzed by SPSS soft ware and compared.FINDINGS: The mean age of our patients was 24.2 4.7 years (16–40 years). The mean gestational age of our patients was 32.4 2.6 weeks. The mean average of maternal heart rate after first dose of betamethasone administration (85.2 8.2) was significantly higher than before treatment (84 8.2) (p= 0.033). But there was no significantly difference between the mean average of maternal systolic and diastolic blood pressure before and after each dose administration. CONCLUSION: Our results show that betamethasone don have any significant effect on systolic and diastolic blood pressure changes in pregnant women but it may increase the mean of maternal heart rate after first dose of injection that this change is transient. Betamethasone has no significant effect on the hemodynamic changes in mother.M Javadian Kutenaie,Z Bouzari,A RouhipourBabol University of Medical Sciencesarticlebetamethasonepreterm laborhemodynamic changesheart rateblood pressureMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 11, Iss 4, Pp 31-35 (2009)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	betamethasone preterm labor hemodynamic changes heart rate blood pressure Medicine R Medicine (General) R5-920
spellingShingle	betamethasone preterm labor hemodynamic changes heart rate blood pressure Medicine R Medicine (General) R5-920 M Javadian Kutenaie, Z Bouzari, A Rouhipour Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
description	BACKGROUND AND OBJECTIVE: Corticosteroids have been used for pregnant women for fetal lung maturation but there are many controversies about their effects and side-effects, the aim of this study was to determine the effects of betamethasone on the hemodynamic changes (heart rate and blood pressure) in pregnant women.METHODS: This clinical trial study performed on 100 pregnant women at risk of preterm delivery between 24-34 weeks of gestation in Yahyanejad hospital in Babol (2006). Betamethasone was injected 12 mg (2 doses with 12 hours interval, IM) and systolic blood pressure, diastolic blood pressure and heart rate were measured before injection (2 times with 5 minute interval) and after first and second dose injection (after each dose 2 times with 2 hours interval). The data were analyzed by SPSS soft ware and compared.FINDINGS: The mean age of our patients was 24.2 4.7 years (16–40 years). The mean gestational age of our patients was 32.4 2.6 weeks. The mean average of maternal heart rate after first dose of betamethasone administration (85.2 8.2) was significantly higher than before treatment (84 8.2) (p= 0.033). But there was no significantly difference between the mean average of maternal systolic and diastolic blood pressure before and after each dose administration. CONCLUSION: Our results show that betamethasone don have any significant effect on systolic and diastolic blood pressure changes in pregnant women but it may increase the mean of maternal heart rate after first dose of injection that this change is transient. Betamethasone has no significant effect on the hemodynamic changes in mother.
format	article
author	M Javadian Kutenaie, Z Bouzari, A Rouhipour
author_facet	M Javadian Kutenaie, Z Bouzari, A Rouhipour
author_sort	M Javadian Kutenaie,
title	Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
title_short	Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
title_full	Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
title_fullStr	Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
title_full_unstemmed	Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor
title_sort	effect of betamethason on maternal hemodynamic changes in preterm labor
publisher	Babol University of Medical Sciences
publishDate	2009
url	https://doaj.org/article/daa31bd5c4ca4d979f5edf4b93ba06db
work_keys_str_mv	AT mjavadiankutenaie effectofbetamethasononmaternalhemodynamicchangesinpretermlabor AT zbouzari effectofbetamethasononmaternalhemodynamicchangesinpretermlabor AT arouhipour effectofbetamethasononmaternalhemodynamicchangesinpretermlabor
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Effect of Betamethason on Maternal Hemodynamic Changes in Preterm Labor

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