Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex

Lipid antigens have been added to the antigenic repertoire in recent years. Here, the authors have identified Mamu-B*098 as a lipopeptide antigen presenting molecule and using structural and biochemical analysis have shown that it has a different antigen binding pocket to previously analysed protein...

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Autores principales:	Daisuke Morita, Yukie Yamamoto, Tatsuaki Mizutani, Takeshi Ishikawa, Juri Suzuki, Tatsuhiko Igarashi, Naoki Mori, Takashi Shiina, Hidetoshi Inoko, Hiroaki Fujita, Kazuhiro Iwai, Yoshimasa Tanaka, Bunzo Mikami, Masahiko Sugita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/daa53f15e3cb4a25a747098318e53ec1
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spelling	oai:doaj.org-article:daa53f15e3cb4a25a747098318e53ec12021-12-02T14:40:14ZCrystal structure of the N-myristoylated lipopeptide-bound MHC class I complex10.1038/ncomms103562041-1723https://doaj.org/article/daa53f15e3cb4a25a747098318e53ec12016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10356https://doaj.org/toc/2041-1723Lipid antigens have been added to the antigenic repertoire in recent years. Here, the authors have identified Mamu-B*098 as a lipopeptide antigen presenting molecule and using structural and biochemical analysis have shown that it has a different antigen binding pocket to previously analysed proteins.Daisuke MoritaYukie YamamotoTatsuaki MizutaniTakeshi IshikawaJuri SuzukiTatsuhiko IgarashiNaoki MoriTakashi ShiinaHidetoshi InokoHiroaki FujitaKazuhiro IwaiYoshimasa TanakaBunzo MikamiMasahiko SugitaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daisuke Morita Yukie Yamamoto Tatsuaki Mizutani Takeshi Ishikawa Juri Suzuki Tatsuhiko Igarashi Naoki Mori Takashi Shiina Hidetoshi Inoko Hiroaki Fujita Kazuhiro Iwai Yoshimasa Tanaka Bunzo Mikami Masahiko Sugita Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
description	Lipid antigens have been added to the antigenic repertoire in recent years. Here, the authors have identified Mamu-B*098 as a lipopeptide antigen presenting molecule and using structural and biochemical analysis have shown that it has a different antigen binding pocket to previously analysed proteins.
format	article
author	Daisuke Morita Yukie Yamamoto Tatsuaki Mizutani Takeshi Ishikawa Juri Suzuki Tatsuhiko Igarashi Naoki Mori Takashi Shiina Hidetoshi Inoko Hiroaki Fujita Kazuhiro Iwai Yoshimasa Tanaka Bunzo Mikami Masahiko Sugita
author_facet	Daisuke Morita Yukie Yamamoto Tatsuaki Mizutani Takeshi Ishikawa Juri Suzuki Tatsuhiko Igarashi Naoki Mori Takashi Shiina Hidetoshi Inoko Hiroaki Fujita Kazuhiro Iwai Yoshimasa Tanaka Bunzo Mikami Masahiko Sugita
author_sort	Daisuke Morita
title	Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
title_short	Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
title_full	Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
title_fullStr	Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
title_full_unstemmed	Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
title_sort	crystal structure of the n-myristoylated lipopeptide-bound mhc class i complex
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/daa53f15e3cb4a25a747098318e53ec1
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Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex

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